The potential therapeutic effect of human umbilical cord mesenchymal stem cell-derived exosomes in bronchopulmonary dysplasia

T Cheng, M Mao, Y Liu, L **e, F Shi, H Liu, X Li - Life Sciences, 2024 - Elsevier
Bronchopulmonary dysplasia (BPD) is a chronic lung disease of preterm infants, with its
incidence rising due to improved survival rates of these infants. BPD results from a …

The Nature and Nurture of Extracellular Vesicle–Mediated Signaling

AH Buck, ENM Nolte-'t Hoen - Annual Review of Genetics, 2024 - annualreviews.org
In the last decade, it has become clear that extracellular vesicles (EVs) are a ubiquitous
component of living systems. These small membrane-enclosed particles can confer diverse …

Stimuli-responsive hydrogel microspheres encapsulated with tumor-cell-derived microparticles for malignant ascites treatment

S Zhu, X Shou, G Kuang, X Kong, W Sun, Q Zhang… - Acta Biomaterialia, 2025 - Elsevier
Tumor-cell-derived microparticles (TMPs) have been recognized as chemotherapeutic drug
carriers and immunomodulators for anti-tumor therapy. Research in the clinical application …

In Silico Tools to Score and Predict Cholesterol–Protein Interactions

A Nguyen, AE Ondrus - Journal of Medicinal Chemistry, 2024 - ACS Publications
Cholesterol is structurally distinct from other lipids, which confers it with singular roles in
membrane organization and protein function. As a signaling molecule, cholesterol engages …

Prominosomes-a particular class of extracellular vesicles containing prominin-1/CD133?

J Karbanová, K Thamm, CA Fargeas, IA Deniz… - Journal of …, 2025 - Springer
Extracellular membrane vesicles (EVs) offer promising values in various medical fields, eg,
as biomarkers in liquid biopsies or as native (or bioengineered) biological nanocarriers in …

[HTML][HTML] Tetraspanin CD9 alters cellular trafficking and endocytosis of tetraspanin CD63, affecting CD63 packaging into small extracellular vesicles

LC Duke, AS Cone, L Sun, DP Dittmer… - Journal of Biological …, 2025 - Elsevier
Small extracellular vesicles (sEVs) are particles secreted from cells that play vital roles both
in normal physiology and in human disease. sEVs are highly enriched in tetraspanin …

Resolving the two-body problem: A postulated role for the V0 sector of the V0V1-ATPase in exosome biogenesis and multivesicular body fate

C D'Souza-Schorey, PD Stahl - Molecular Biology of the Cell, 2025 - molbiolcell.org
Because the discovery of the multivesicular body (MVB) as the origin of secreted vesicles or
exosomes, the question arose and still looms—what distinguishes an MVB destined for …

Plasma membrane remodelling in GM2 gangliosidoses drives synaptic dysfunction

AS Nicholson, DA Priestman, R Antrobus… - bioRxiv, 2024 - biorxiv.org
Glycosphingolipids (GSL) are important bioactive components of cellular membranes.
Complex GSLs, containing one or more sialic acid residues are known as gangliosides and …

Exosome: an overview on enhanced biogenesis by small molecules

A Bavafa, M Izadpanahi, E Hosseini… - Naunyn-Schmiedeberg's …, 2025 - Springer
Exosomes are extracellular vesicles that received attention for their potential use in the
treatment of various injuries. They communicate intercellularly by transferring genetic and …

[HTML][HTML] Extracellular Vesicles as Tools for Crossing the Blood–Brain Barrier to Treat Lysosomal Storage Diseases

G Lerussi, V Villagrasa-Araya, M Moltó-Abad… - Life, 2025 - mdpi.com
Extracellular vesicles (EVs) are nanosized, membrane-bound structures that have emerged
as promising tools for drug delivery, especially in the treatment of lysosomal storage …