Inadequate or excessive nutrient consumption leads to oxidative stress, which may disrupt
oxidative homeostasis, activate a cascade of molecular pathways, and alter the metabolic …

ABSTRACT CONTEXT AND OBJECTIVE: Diet is an important modifiable factor involved in
obesity-induced inflammation. We reviewed clinical trials that assessed the effect of …

Postprandial IL-1β surges are predominant in the white adipose tissue (WAT), but its
consequences are unknown. Here, we investigate the role of IL-1β in WAT energy storage …

Cytokines of the IL-1 family are important modulators of obesity-induced inflammation and
the development of systemic insulin resistance. Here we show that IL-1 family member IL-37 …

Macronutrient metabolism is a highly orchestrated process, with adipose tissue and liver
each playing central roles in nutrient uptake, processing, transport, and storage. These 2 …

Obesity is an excessive accumulation of body fat that may be harmful to health. Today,
obesity is a major public health problem, affecting in greater or lesser proportion all …

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities characterized by central
obesity, dyslipidemias, hypertension, high fasting glucose, chronic low-grade inflammation …

Context: Postprandial endotoxemia is a metabolic risk factor, which has been shown to
originate from the intestinal absorption of gut lipopolysaccharides (LPS) using …

Objective Chronic low-grade inflammation has been associated with insulin resistance,
diabetes, atherosclerosis, obesity, and metabolic syndrome (MetS). A proinflammatory …

Background: Previous data support the benefits of reducing dietary saturated fatty acids
(SFAs) on insulin resistance (IR) and other metabolic risk factors. However, whether the IR …