Natural products of pentacyclic triterpenoids: from discovery to heterologous biosynthesis
Y Li, J Wang, L Li, W Song, M Li, X Hua, Y Wang… - Natural product …, 2023 - pubs.rsc.org
Covering: up to 2022 Pentacyclic triterpenoids are important natural bioactive substances
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …
A review of the microbial production of bioactive natural products and biologics
JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …
also known as natural products. Natural products have been a prolific source and an …
Emerging technologies in algal biotechnology: toward the establishment of a sustainable, algae-based bioeconomy
Mankind has recognized the value of land plants as renewable sources of food, medicine,
and materials for millennia. Throughout human history, agricultural methods were …
and materials for millennia. Throughout human history, agricultural methods were …
Engineering yeast for the production of plant terpenoids using synthetic biology approaches
Covering: 2011–2022 The low amounts of terpenoids produced in plants and the difficulty in
synthesizing these complex structures have stimulated the production of terpenoid …
synthesizing these complex structures have stimulated the production of terpenoid …
Recent advances in triterpenoid pathway elucidation and engineering
Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …
Strategies to diversify natural products for drug discovery
G Li, HX Lou - Medicinal research reviews, 2018 - Wiley Online Library
Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …
microorganisms that play a pivotal role in drug discovery due to their immense structural …
Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism
The amount of cholesterol made by many plants is not negligible. Whereas
cholesterogenesis in animals was elucidated decades ago, the plant pathway has remained …
cholesterogenesis in animals was elucidated decades ago, the plant pathway has remained …
De novo production of the plant-derived alkaloid strictosidine in yeast
The monoterpene indole alkaloids are a large group of plant-derived specialized
metabolites, many of which have valuable pharmaceutical or biological activity. There are∼ …
metabolites, many of which have valuable pharmaceutical or biological activity. There are∼ …
Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis
Horse chestnut (Aesculus chinensis) is an important medicinal tree that contains various
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …
Synthesizing ginsenoside Rh2 in Saccharomyces cerevisiae cell factory at high-efficiency
Synthetic biology approach has been frequently applied to produce plant rare bioactive
compounds in microbial cell factories by fermentation. However, to reach an ideal …
compounds in microbial cell factories by fermentation. However, to reach an ideal …