Background Current guidelines target low-density lipoprotein cholesterol (LDL-C)
concentrations to reduce atherosclerotic cardiovascular disease (ASCVD) risk, and yet …

Cardiovascular disease (CVD) is the main cause of death globally and responsible for the
second highest number of deaths in Canada. Medical advancements in the treatment of …

Background Genetic, observational, and clinical intervention studies indicate that circulating
levels of triglycerides and cholesterol transported in triglyceride-rich lipoproteins (remnant …

Background Elevated triglyceride-rich lipoprotein (TRL) and small-dense low-density
lipoprotein (sdLDL) particles are hallmarks of atherogenic dyslipidemia, and their …

Background Elevated plasma levels of direct low‐density lipoprotein cholesterol (LDL‐C),
small dense LDL‐C (sdLDL‐C), low‐density lipoprotein (LDL) triglycerides, triglycerides …

Aims We tested the hypothesis that high directly measured remnant cholesterol is
associated with increased risk of ischaemic heart disease (IHD) and myocardial infarction …

Aims/hypothesis Elevated remnant cholesterol is observationally and causally associated
with increased risk of atherosclerotic cardiovascular disease (ASCVD) in the general …

Abstract Purpose of Review Implementation of intensive LDL cholesterol (LDL-C) lowering
strategies and recognition of the role of triglyceride-rich lipoproteins (TRL) in atherosclerosis …

Abnormal lipid metabolism leads to the development of hyperlipidemia, a common cause of
multiple chronic disorders, including cardiovascular disease (CVD), obesity, diabetes, and …

Low-density lipoprotein cholesterol is a well-known causal factor for atherosclerotic
cardiovascular disease, and is the primary target of lipid-lowering therapy. There is …