Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

The mechanism (s) of how bacteria acquire tolerance and then resistance to antibiotics
remains poorly understood. Here, we show that glucose abundance decreases …

Essential oils (EOs) and their individual volatile organic constituents have been an inherent
part of our civilization for thousands of years. They are widely used as fragrances in …

Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of
“post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the …

Bacteria colonize almost all parts of the human body and can differ significantly. However,
the population level transcriptomics measurements can only describe the average bacteria …

Microbial communities are composed of cells of varying metabolic capacity, and regularly
include auxotrophs that lack essential metabolic pathways. Through analysis of auxotrophs …

Antibiotic-induced gut dysbiosis (AID) is a frequent and serious side effect of antibiotic use
and mitigating this dysbiosis is a critical therapeutic target. We propose that the host diet can …

Several promising strategies based on combining or cycling different antibiotics have been
proposed to increase efficacy and counteract resistance evolution, but we still lack a deep …