Brain nuclear receptors and cardiovascular function

M Wang, Y Yang, Y Xu - Cell & Bioscience, 2023 - Springer
Brain–heart interaction has raised up increasing attentions. Nuclear receptors (NRs) are
abundantly expressed in the brain, and emerging evidence indicates that a number of these …

Constitutive androstane receptor: a peripheral and a neurovascular stress or environmental sensor

F Oliviero, C Lukowicz, B Boussadia, I Forner-Piquer… - Cells, 2020 - mdpi.com
Xenobiotic nuclear receptors (NR) are intracellular players involved in an increasing number
of physiological processes. Examined and characterized in peripheral organs where they …

Triclocarban exposure affects mouse oocyte in vitro maturation through inducing mitochondrial dysfunction and oxidative stress

ZM Ding, MJ Ahmad, F Meng, F Chen, YS Wang… - Environmental …, 2020 - Elsevier
Abstract Triclocarban (TCC), a broad-spectrum lipophilic antibacterial agent, is the main
ingredient of personal and health care products. Nonetheless, its ubiquitous presence in the …

[HTML][HTML] Triclocarban triggers osteoarthritis via DNMT1-mediated epigenetic modification and suppression of COL2A in cartilage tissues

Y Zhang, L He, Y Yang, J Cao, Z Su, B Zhang… - Journal of Hazardous …, 2023 - Elsevier
Triclocarban (TCC) is a widely used environmental endocrine-disrupting chemical (EDC).
Articular injury of EDCs has been reported; however, whether and how TCCs damage the …

[HTML][HTML] Integrated multi-omics approaches reveal the neurotoxicity of triclocarban in mouse brain

Q Song, C Hu, X Zhang, P Ji, Y Li, H Peng… - Environment …, 2024 - Elsevier
Triclocarban (TCC) is an antimicrobial ingredient that commonly incorporated in many
household and personal care products, raising public concerns about its potential health …

Kynurenine/aryl hydrocarbon receptor modulates mitochondria-mediated oxidative stress and neuronal apoptosis in experimental intracerebral hemorrhage

R Ren, Y Fang, P Sherchan, Q Lu… - Antioxidants & redox …, 2022 - liebertpub.com
Aims: Oxidative stress and neuronal apoptosis play crucial roles in the pathological
processes of secondary injury after intracerebral hemorrhage (ICH). Aryl hydrocarbon …

Effect-directed analysis for revealing aryl hydrocarbon receptor agonists in sediment samples from an electronic waste recycling town in China

Q Ma, Y Liu, X Yang, Y Guo, T **ang, Y Wang… - Environmental …, 2022 - Elsevier
Exposure to electronic and electrical waste (e-waste) has been related to a few adverse
health effects. In this study, sediment samples from an e-waste recycling town in China were …

Linking emerging contaminants exposure to adverse health effects: Crosstalk between epigenome and environment

MN Alam, UM Shapla, H Shen… - Journal of Applied …, 2021 - Wiley Online Library
Environmental epigenetic findings shed new light on the roles of epigenetic regulations in
environmental exposure‐induced toxicities or disease susceptibilities. Currently …

Nuclear receptors in myocardial and cerebral ischemia—mechanisms of action and therapeutic strategies

J Rzemieniec, L Castiglioni, P Gelosa… - International Journal of …, 2021 - mdpi.com
Nearly 18 million people died from cardiovascular diseases in 2019, of these 85% were due
to heart attack and stroke. The available therapies although efficacious, have narrow …

Amorfrutin B protects mouse brain neurons from hypoxia/ischemia by inhibiting apoptosis and autophagy processes through gene methylation-and miRNA-dependent …

K Przepiórska, A Wnuk, C Beyer, M Kajta - Molecular Neurobiology, 2023 - Springer
Amorfrutin B is a selective modulator of the PPARγ receptor, which has recently been
identified as an effective neuroprotective compound that protects brain neurons from hypoxic …