The RNA world concept is one of the most fundamental pillars of the origin of life theory,–. It
predicts that life evolved from increasingly complex self-replicating RNA molecules,,. The …

Homochirality is a signature of life on Earth, yet its origins remain an unsolved puzzle.
Achieving homochirality is essential for a high-yielding prebiotic network capable of …

Compartmentalization is crucial for the evolution of life. Present-day phospholipid
membranes exhibit a high level of complexity and species-dependent homochirality, the so …

Coded ribosomal peptide synthesis could not have evolved unless its sequence and amino
acid–specific aminoacylated tRNA substrates already existed. We therefore wondered …

Extant biology uses RNA to record genetic information and proteins to execute biochemical
functions. Nucleotides are translated into amino acids via transfer RNA in the central dogma …

The world in which we live is homochiral. The ribose units that form the backbone of DNA
and RNA are all D‐configured and the encoded amino acids that comprise the proteins of all …

Modern life is essentially homochiral, containing D-sugars in nucleic acid backbones and L-
amino acids in proteins. Since coded proteins are theorized to have developed from a …

Homochirality is a hallmark of life on Earth. To achieve and maintain homochirality within a
prebiotic network, the presence of an environmental factor acting as a chiral agent and …

Biological systems are homochiral, raising the question of how a racemic mixture of
prebiotically synthesized biomolecules could attain a homochiral state at the network level …

Translation according to the genetic code is made possible by selectivity both in
aminoacylation of tRNA and in anticodon/codon recognition. In extant biology, tRNAs are …