Hepatocellular carcinoma (HCC) is associated with chronic inflammation and fibrosis arising
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …

Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …

Liver metastasis is a major cause of death in patients with colorectal cancer (CRC). Fatty
liver promotes liver metastasis, but the underlying mechanism remains unclear. We …

Perturbations in metabolic processes are associated with diseases such as obesity, type 2
diabetes mellitus, certain infections and some cancers. A resurgence of interest in creatine …

Idiosyncratic drug‐induced liver injury (DILI) is a rare, often difficult‐to‐predict adverse
reaction with complex pathomechanisms. However, it is now evident that certain forms of …

Simple Summary The concentration of uric acid in blood is sex-, age-and diet-dependent
and is maintained close to its maximal solubility, indicating that it plays some important role …

Nonalcoholic fatty liver disease (NAFLD) enhances the growth and recurrence of colorectal
cancer (CRC) liver metastasis. With the rising prevalence of NAFLD, a better understanding …

Background & Aims Chemotherapy-associated liver injury (CALI) increases the risk of liver
resection and may prejudice further surgery and chemotherapy. The reversibility of CALI is …

Background Ischemia reperfusion injury (IRI) has been shown to increase the risk of tumor
recurrence after liver surgery. Also, nonalcoholic fatty liver disease (NAFLD) is associated …

Steatotic liver, characterized by the accumulation of fat in the liver, poses significant health
risks including metabolic dysfunction-associated steatotic liver disease (MASLD) and an …