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Reaction-diffusion model as a framework for understanding biological pattern formation
S Kondo, T Miura - science, 2010 - science.org
The Turing, or reaction-diffusion (RD), model is one of the best-known theoretical models
used to explain self-regulated pattern formation in the develo** animal embryo. Although …
used to explain self-regulated pattern formation in the develo** animal embryo. Although …
Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases
The processes of bone growth, modeling, and remodeling determine the structure, mass,
and biomechanical properties of the skeleton. Dysregulated bone resorption or bone …
and biomechanical properties of the skeleton. Dysregulated bone resorption or bone …
Stem cell differentiation trajectories in Hydra resolved at single-cell resolution
INTRODUCTION The cnidarian polyp Hydra undergoes continual self-renewal and is
capable of whole-body regeneration from a small piece of tissue. The stem cell populations …
capable of whole-body regeneration from a small piece of tissue. The stem cell populations …
Distinct antimicrobial peptide expression determines host species-specific bacterial associations
Animals are colonized by coevolved bacterial communities, which contribute to the host's
health. This commensal microbiota is often highly specific to its host-species, inferring strong …
health. This commensal microbiota is often highly specific to its host-species, inferring strong …
The evolution of the Wnt pathway
TW Holstein - Cold Spring Harbor Perspectives in …, 2012 - cshperspectives.cshlp.org
Wnt genes are important regulators of embryogenesis and cell differentiation in vertebrates
and insects. New data revealed by comparative genomics have now shown that members of …
and insects. New data revealed by comparative genomics have now shown that members of …
[HTML][HTML] Multiple Wnts are involved in Hydra organizer formation and regeneration
Wnt genes and β-Catenin signaling are involved in axial patterning processes in vertebrate
embryogenesis in setting up the Spemann–Mangold organizer in amphibian embryos. An …
embryogenesis in setting up the Spemann–Mangold organizer in amphibian embryos. An …
Model systems for regeneration: Hydra
The freshwater polyp Hydra provides a potent model system for investigating the conditions
that promote wound healing, reactivation of a developmental process and, ultimately …
that promote wound healing, reactivation of a developmental process and, ultimately …
[HTML][HTML] Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response
Regeneration is widespread throughout the animal kingdom, but our molecular
understanding of this process in adult animals remains poorly understood. Wnt/β-catenin …
understanding of this process in adult animals remains poorly understood. Wnt/β-catenin …
Unifying principles of regeneration I: Epimorphosis versus morphallaxis
K Agata, Y Saito, E Nakajima - Development, growth & …, 2007 - Wiley Online Library
Because research on regeneration has a long history, some classic definitions and concepts
about regeneration which were established in earlier times have been retained without …
about regeneration which were established in earlier times have been retained without …
[HTML][HTML] Why polyps regenerate and we don't: towards a cellular and molecular framework for Hydra regeneration
TCG Bosch - Developmental biology, 2007 - Elsevier
The basis for Hydra's enormous regeneration capacity is the “stem cellness” of its epithelium
which continuously undergoes self-renewing mitotic divisions and also has the option to …
which continuously undergoes self-renewing mitotic divisions and also has the option to …