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Germline Testing and Somatic Tumor Testing for BRCA1/2 Pathogenic Variants in Ovarian Cancer: What Is the Optimal Sequence of Testing?
JS Kwon, AV Tinker, J Santos, K Compton… - JCO Precision …, 2022 - ascopubs.org
PURPOSE In 2020, ASCO recommended that all women with epithelial ovarian cancer have
germline testing for BRCA1/2 mutations, and those without a germline pathogenic variant …
germline testing for BRCA1/2 mutations, and those without a germline pathogenic variant …
Chronic lymphocytic leukemia IGHV somatic hypermutation detection by targeted capture next-generation sequencing
Background Somatic hypermutation (SHM) status of the immunoglobulin heavy variable
(IGHV) gene plays a crucial role in determining the prognosis and treatment of patients with …
(IGHV) gene plays a crucial role in determining the prognosis and treatment of patients with …