Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients

JZ Wang, AP Landry, DR Raleigh, F Sahm… - Neuro …, 2024 - academic.oup.com
Meningiomas are the most common primary intracranial tumors in adults and are increasing
in incidence due to the aging population and increased access to neuroimaging. While most …

Molecular alterations in meningioma: prognostic and therapeutic perspectives

C Birzu, M Peyre, F Sahm - Current opinion in oncology, 2020 - journals.lww.com
The mutational landscape of meningioma has expanded following the use of the new
genetic sequencing approaches. Novel mutations have been characterized and reveal their …

Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution

CHG Lucas, K Mirchia, K Seo, H Najem, WC Chen… - Nature …, 2024 - nature.com
Intratumor heterogeneity underlies cancer evolution and treatment resistance, but targetable
mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the …

A molecularly integrated grade for meningioma

J Driver, SE Hoffman, S Tavakol, E Woodward… - Neuro …, 2022 - academic.oup.com
Background Meningiomas are the most common primary intracranial tumor in adults.
Clinical care is currently guided by the World Health Organization (WHO) grade assigned to …

Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies

JC Bayley, CC Hadley, AO Harmanci, AS Harmanci… - Science …, 2022 - science.org
One-fifth of meningiomas classified as benign by World Health Organization (WHO)
histopathological grading will behave malignantly. To better diagnose these tumors, several …

Microscopic mechanism for a higher-spin Kitaev model

PP Stavropoulos, D Pereira, HY Kee - Physical review letters, 2019 - APS
The spin S= 1 2 Kitaev honeycomb model has attracted significant attention since emerging
candidate materials have provided a playground to test non-Abelian anyons. The Kitaev …

Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses

WC Chen, A Choudhury, MW Youngblood… - Nature medicine, 2023 - nature.com
Surgery is the mainstay of treatment for meningioma, the most common primary intracranial
tumor, but improvements in meningioma risk stratification are needed and indications for …

Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma

ST Magill, HN Vasudevan, K Seo… - Nature …, 2020 - nature.com
Meningiomas are the most common primary intracranial tumors, but the molecular drivers of
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …

Radiotherapy for meningiomas

WC Chen, HK Perlow, A Choudhury, MP Nguyen… - Journal of neuro …, 2022 - Springer
Meningiomas are the most common primary central nervous system neoplasm. Despite
promising recent progress in elucidating the genomic landscape and underlying biology of …

Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features

A Choudhury, WC Chen, CHG Lucas… - Neuro …, 2023 - academic.oup.com
Background Meningiomas, the most common primary intracranial tumors, can be separated
into 3 DNA methylation groups with distinct biological drivers, clinical outcomes, and …