Free radical damage is linked to formation of many degenerative diseases, including cancer,
cardiovascular disease, cataracts, and aging. Excessive reactive oxygen species (ROS) …

Free radical production occurs continuously in all cells as part of normal cellular function.
However, excess free radical production originating from endogenous or exogenous …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Tocopherols and tocotrienols (vitamin E), ascorbic acid (vitamin C), and the carotenoids
react with free radicals, notably peroxyl radicals, and with singlet molecular oxygen (1O2) …

Background The oxidative modification of low-density lipoproteins increases their
incorporation into the arterial intima, an essential step in atherogenesis. Although dietary …

Uric acid, or more correctly (at physiological pH values), its monoanion urate, is traditionally
considered to be a metabolically inert end-product of purine metabolism in man, without any …

Background Interest in the antioxidant vitamin E as a possible protective nutrient against
coronary disease has intensified with the recognition that oxidized low-density lipoprotein …

Increased fruit and vegetable consumption is associated with a decreased incidence of
cardiovascular diseases, cancer, and other chronic diseases. The beneficial health effects of …

This article is a brief overview of the mechanisms of production of reactive oxygen species in
biologic systems, and the various antioxidant defense systems that provide protection …

Free radical oxidative stress has been implicated in the pathogenesis of a variety of human
diseases. Natural antioxidant defences have been found to be defective in many of the same …