Optical coherence tomography (OCT): a brief look at the uses and technological evolution of ophthalmology

M Zeppieri, S Marsili, ES Enaholo, AO Shuaibu… - Medicina, 2023 - mdpi.com
Medical imaging is the mainstay of clinical diagnosis and management. Optical coherence
tomography (OCT) is a non-invasive imaging technology that has revolutionized the field of …

Measuring the contributions of basal laminar deposit and Bruch's membrane in age-related macular degeneration

AA Sura, L Chen, JD Messinger… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: Basal laminar deposit (BLamD) is a consistent finding in age-related macular
degeneration (AMD). We quantified BLamD thickness, appearance, and topography in eyes …

[HTML][HTML] Hyperreflective foci, optical coherence tomography progression indicators in age-related macular degeneration, include transdifferentiated retinal pigment …

D Cao, B Leong, JD Messinger, D Kar… - … & visual science, 2021 - tvst.arvojournals.org
Purpose: By optical coherence tomography (OCT) imaging, hyperreflective foci (HRF)
indicate progression risk for advanced age-related macular degeneration (AMD) and are in …

[PDF][PDF] 内窥光学相干层析成像的研究进展与应用

张璇晔, 朱疆 - Chinese Journal of Lasers, 2023 - researching.cn
摘要光学相干层析成像(OCT) 技术是一种无标记的三维成像技术, 具有分辨率高,
成像速度快等优点. 内窥成像是OCT 技术的一个重要应用, 它能够通过微型探头和内窥导管获得 …

[HTML][HTML] Biometrics, impact, and significance of basal linear deposit and subretinal drusenoid deposit in age-related macular degeneration

L Chen, JD Messinger, D Kar… - … & Visual Science, 2021 - tvst.arvojournals.org
Purpose: Basal linear deposit (BLinD) is a thin layer of soft drusen material. To elucidate the
biology of extracellular deposits conferring age-related macular degeneration (AMD) …

[HTML][HTML] Ultrahigh resolution OCT markers of normal aging and early age-related macular degeneration

S Chen, O Abu-Qamar, D Kar, JD Messinger… - Ophthalmology …, 2023 - Elsevier
Purpose Ultrahigh resolution spectral domain-OCT (UHR SD-OCT) enables in vivo
visualization of micrometric structural markers which differentially associate with normal …

Deep-learning-based automated measurement of outer retinal layer thickness for use in the assessment of age-related macular degeneration, applicable to both …

J Lu, Y Cheng, FE Hiya, M Shen, G Herrera… - Biomedical optics …, 2023 - opg.optica.org
Effective biomarkers are required for assessing the progression of age-related macular
degeneration (AMD), a prevalent and progressive eye disease. This paper presents a deep …

[HTML][HTML] Visible light optical coherence tomography (OCT) quantifies subcellular contributions to outer retinal band 4

T Zhang, AM Kho, G Yiu… - … vision science & …, 2021 - iovs.arvojournals.org
Purpose: To use visible light optical coherence tomography (OCT) to investigate subcellular
reflectivity contributions to the outermost (4th) of the retinal hyperreflective bands visualized …

In vivo Morphometry of Inner Plexiform Layer (IPL) Stratification in the Human Retina With Visible Light Optical Coherence Tomography

T Zhang, AM Kho, VJ Srinivasan - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
From the bipolar cells to higher brain visual centers, signals in the vertebrate visual system
are transmitted along parallel on and off pathways. These two pathways are spatially …

[HTML][HTML] Update on Clinical Trial Endpoints in Gene Therapy Trials for Inherited Retinal Diseases

JM Igoe, BL Lam, NZ Gregori - Journal of clinical medicine, 2024 - mdpi.com
Inherited retinal diseases (IRDs) encompass a wide spectrum of rare conditions
characterized by diverse phenotypes associated with hundreds of genetic variations, often …