[HTML][HTML] Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment

V Gandin, P Khalkar, J Braude… - Free Radical Biology and …, 2018 - Elsevier
Selenium (Se)-containing compounds have attracted a growing interest as anticancer
agents over recent decades, with mounting reports demonstrating their high efficacy and …

Selenium compounds as therapeutic agents in cancer

AP Fernandes, V Gandin - Biochimica et Biophysica Acta (BBA)-General …, 2015 - Elsevier
Background With cancer cells encompassing consistently higher production of reactive
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …

Selenium species: current status and potentials in cancer prevention and therapy

HW Tan, HY Mo, ATY Lau, YM Xu - International journal of molecular …, 2018 - mdpi.com
Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …

Organoselenium and organotellurium compounds: toxicology and pharmacology

CW Nogueira, G Zeni, JBT Rocha - Chemical reviews, 2004 - ACS Publications
Organoselenium compounds have found such wide utility because of their effects on an
extraordinary number of very different reactions, including many carbon-carbon bond …

Recent developments in the synthesis of biologically relevant selenium-containing scaffolds

B Banerjee, M Koketsu - Coordination Chemistry Reviews, 2017 - Elsevier
Recent, many methods have been reported for the synthesis of selenium-containing
bioactive scaffolds because of their interesting reactivity and potential pharmaceutical …

[HTML][HTML] A review on selenium nanoparticles and their biomedical applications

KK Karthik, BV Cheriyan, S Rajeshkumar… - Biomedical …, 2024 - Elsevier
Nanotechnology has enormous promise for a wide range of applications in biology.
Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing …

Biologically significant selenium-containing heterocycles

M Ninomiya, DR Garud, M Koketsu - Coordination Chemistry Reviews, 2011 - Elsevier
Selenium represents an essential element for organisms as various diseases can result from
selenium deficiency. As a consequence, selenium-containing heterocycles are of …

Voyage of selenium from environment to life: Beneficial or toxic?

M Banerjee, D Chakravarty, P Kalwani… - Journal of Biochemical …, 2022 - Wiley Online Library
Selenium (Se), a naturally occurring metalloid, is an essential micronutrient for life as it is
incorporated as selenocysteine in proteins. Although beneficial at low doses, Se is …

Selenium compounds and apoptotic modulation: a new perspective in cancer therapy

C Sanmartin, D Plano, JA Palop - Mini reviews in medicinal …, 2008 - ingentaconnect.com
Recent epidemiological studies have demonstrated that selenium may be an effective
chemopreventive and anticancer agent with a broad spectrum against several human …

Understanding the redox biology of selenium in the search of targeted cancer therapies

JM Stolwijk, R Garje, JC Sieren, GR Buettner… - Antioxidants, 2020 - mdpi.com
Selenium (Se) is an essential trace nutrient required for optimal human health. It has long
been suggested that selenium has anti-cancer properties. However, clinical trials have …