While complex physiological mechanisms exist to regulate and optimize tissue oxygenation
under various conditions, clinical and experimental evidence indicates that anaemia …

Myelotoxicity is one of the most common treatment-related adverse events for patients
receiving systemic antineoplastic therapy or radiotherapy to bone marrow–producing …

Importance There is marked variability in red blood cell (RBC) transfusion during the
intraoperative period. The development and implementation of existing clinical practice …

Objective To assess the effect of red blood cell (RBC) transfusion on quality of life in acutely
anaemic women after postpartum haemorrhage. Design Randomised non‐inferiority trial …

Background Transfusion of blood components continues to be an important therapeutic
resource into the 21st century. Between 5 and 58% of transfusions carried out are estimated …

Background: According to the US Food and Drug Administration Center for Biologics
Evaluation and Research, health care systems have been experiencing blood transfusion …

Anemia and red blood cell (RBC) transfusion occur frequently in hospitalized patients with
cardiac disease. In this narrative review, we report the epidemiology of anemia and RBC …

As transfusion is a commonly identified overused intervention, there is a clear gap between
evidence‐based and clinical practice. To close this gap, there is not only a need for …

BACKGROUND Evaluating the appropriateness of red blood cell (RBC) transfusion requires
labor‐intensive medical chart audits and expert adjudication. We sought to determine the …

The work forming the basis for this PhD thesis was carried out during my employment as a
Research Fellow at the Department of Intensive Care, Copenhagen University Hospital …