Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Delivery technologies for cancer immunotherapy

RS Riley, CH June, R Langer, MJ Mitchell - Nature reviews Drug …, 2019 - nature.com
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

Biomimetic nanotechnology toward personalized vaccines

J Zhou, AV Kroll, M Holay, RH Fang… - Advanced …, 2020 - Wiley Online Library
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …

Mimicking biological functionality with polymers for biomedical applications

JJ Green, JH Elisseeff - Nature, 2016 - nature.com
The vast opportunities for biomaterials design and functionality enabled by mimicking nature
continue to stretch the limits of imagination. As both biological understanding and …

Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells

AS Cheung, DKY Zhang, ST Koshy, DJ Mooney - Nature biotechnology, 2018 - nature.com
Therapeutic ex vivo T-cell expansion is limited by low rates and T-cell products of limited
functionality. Here we describe a system that mimics natural antigen-presenting cells (APCs) …

Advancing to the era of cancer immunotherapy

Y Wang, M Wang, HX Wu, RH Xu - Cancer Communications, 2021 - Wiley Online Library
Cancer greatly affects the quality of life of humans worldwide and the number of patients
suffering from it is continuously increasing. Over the last century, numerous treatments have …

Cell membrane-derived nanomaterials for biomedical applications

RH Fang, Y Jiang, JC Fang, L Zhang - Biomaterials, 2017 - Elsevier
The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal

E Ben-Akiva, RA Meyer, H Yu, JT Smith, DM Pardoll… - Science …, 2020 - science.org
The design of next-generation nanobiomaterials requires precise engineering of both
physical properties of the core material and chemical properties of the material's surface to …