Background: Comorbidity is an area of increasing interest in multiple sclerosis (MS).
Objective: The objective of this review is to estimate the incidence and prevalence of …

Multiple sclerosis (MS) is a chronic immune-mediated demyelinating disease of the central
nervous system characterized by relapses and remissions. The risk of acquiring this …

Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin
and joint manifestations affecting approximately 2% of the population. In this first of 5 …

We have evaluated prospectively the prevalence of other autoimmune disorders in
outpatient clinic in 3069 consecutive patients with diagnosed chronic autoimmune thyroiditis …

BACKGROUND: Common autoimmune disorders tend to coexist in the same subjects and to
cluster in families. METHODS: We performed a cross-sectional multicenter study of 3286 …

Biological barriers are essential for the maintenance of homeostasis in health and disease.
Breakdown of the intestinal barrier is an essential aspect of the pathophysiology of …

Recent genetic studies have revealed shared immunological mechanisms in several
immune-related disorders that further our understanding of the development and …

Importance Tumor necrosis factor (TNF) inhibitors are common therapies for certain
autoimmune diseases, such as rheumatoid arthritis. An association between TNF inhibitor …

Background A primary characteristic of complex genetic diseases is that affected individuals
tend to cluster in families (that is, familial aggregation). Aggregation of the same …

CD8+ T‐cell deficiency is a feature of many chronic autoimmune diseases, including
multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, Sjögren′ s …