[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

Obesity-induced neuroinflammation: beyond the hypothalamus

O Guillemot-Legris, GG Muccioli - Trends in neurosciences, 2017 - cell.com
Obesity is now a worldwide health issue. Far from being limited to weight gain, obesity is
generally associated with low-grade inflammation and with a cluster of disorders collectively …

Diseases, disorders, and comorbidities of interoception

B Bonaz, RD Lane, ML Oshinsky, PJ Kenny… - Trends in …, 2021 - cell.com
Interoception, the sense of the body's internal physiological state, underpins homeostatic
reflexes, motivational states, and sensations contributing to emotional experiences. The …

Food for thought: how nutrition impacts cognition and emotion

SJ Spencer, A Korosi, S Layé, B Shukitt-Hale… - npj Science of …, 2017 - nature.com
More than one-third of American adults are obese and statistics are similar worldwide.
Caloric intake and diet composition have large and lasting effects on cognition and emotion …

[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

[HTML][HTML] Supra-additive effects of combining fat and carbohydrate on food reward

AG DiFeliceantonio, G Coppin, L Rigoux… - Cell metabolism, 2018 - cell.com
Post-ingestive signals conveying information about the nutritive properties of food are critical
for regulating ingestive behavior. Here, using an auction task concomitant to fMRI scanning …

[HTML][HTML] The cafeteria diet: A standardized protocol and its effects on behavior

JF Lalanza, EMS Snoeren - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Obesity is a major health risk, with junk food consumption playing a central role in weight
gain, because of its high palatability and high-energy nutrients. The Cafeteria (CAF) diet …

Food and food groups in inflammatory bowel disease (IBD): The design of the groningen anti-inflammatory diet (GrAID)

MJE Campmans-Kuijpers, G Dijkstra - Nutrients, 2021 - mdpi.com
Diet plays a pivotal role in the onset and course of inflammatory bowel disease (IBD).
Patients are keen to know what to eat to reduce symptoms and flares, but dietary guidelines …

Gut to brain dysbiosis: mechanisms linking western diet consumption, the microbiome, and cognitive impairment

EE Noble, TM Hsu, SE Kanoski - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
Consumption of a Western Diet (WD) that is high in saturated fat and added sugars
negatively impacts cognitive function, particularly mnemonic processes that rely on the …

A four-day Western-style dietary intervention causes reductions in hippocampal-dependent learning and memory and interoceptive sensitivity

T Attuquayefio, RJ Stevenson, MJ Oaten, HM Francis - PLoS One, 2017 - journals.plos.org
In animals, a Western style diet–high in saturated fat and added sugar–causes impairments
in hippocampal-dependent learning and memory (HDLM) and perception of internal bodily …