Polysialic acid (PSA) is a straight-chain homoglycan linked by N-acetylneuraminic acid
monomers via α-2, 8-or α-2, 9-glycosidic bonds. As a negatively charged non …

Abstract World Health Organisation (WHO) delineated cancer as one of the foremost
reasons for mortality with 10 million deaths in the year 2020. Early diagnosis and effective …

Vascular disorders, characterized by vascular endothelial dysfunction combined with
inflammation, are correlated with numerous fatal diseases, such as coronavirus disease-19 …

Polysialic acid (polySia, PSA) is a unique constituent of the glycocalyx on the surface of
bacterial and vertebrate cells. In vertebrates, its biosynthesis is highly regulated, not only in …

Antifouling polymers are materials that can resist nonspecific interactions with cells, proteins,
and other biomolecules. Typically, they are hydrophilic polymers with polar or charged …

In this paper, a novel redox-responsive nanoparticles has been designed for targeted
delivery of docetaxel (DTX). Chondroitin sulfate (CS) was used to construct the …

In this work, we developed polysialic acid (PSA) modified zein nanoparticles for targeted
delivery of honokiol (HNK) to enhance drug delivery efficiency and specific biodistribution at …

Mononuclear phagocytes are efficient drug delivery targets for cancers owing to their
cancerous tissue-accumulating nature. As receptors of sialic acid, Siglecs (sialic acid …

The excessive production and deposition of amyloid-β (Aβ) is one of the most important
etiologies of Alzheimer's disease (AD). The interaction between Aβ and metal ions produces …

Combined administration of drugs can improve efficacy and reduce toxicity; therefore, this
combination approach has become a routine method in cancer therapy. The main …