Objective Research and clinical interest in irritability have been on the rise in recent years.
Yet several questions remain about the status of irritability in psychiatry, including whether …

Although irritability is among the most common reasons that children and adolescents are
brought for psychiatric care, there are few effective treatments. Developmentally sensitive …

The National Institute of Mental Health (NIMH) proposed the Research Domain Criteria
(RDoC) initiative as an alternate way to organize research of mental illnesses, by looking at …

Irritability, defined as proneness to anger that may impair an individual's functioning, is
common in youths. There has been a recent upsurge in relevant research. The authors …

Background Irritability is one of the most common reasons for referral to child and
adolescent mental health services and is the main characteristic of the new diagnosis of …

Objective Irritability is a transdiagnostic indicator of child and adolescent internalizing and
externalizing problems that is measurable from early life. The objective of this systematic …

Irritability is a common and impairing clinical presentation in children and adolescents.
Despite its significant public health impact, irritability remains an elusive construct. Chronic …

The arrival of the Journal's 175th anniversary occurs at a time of recent advances in
research, providing an ideal opportunity to present a neurodevelopmental roadmap for …

Objective The importance of dimensional approaches is widely recognized, but an empirical
base for clinical application is lacking. This is particularly true for irritability, a dimensional …

Importance Suicidal ideation and suicide attempt (suicidality) are common in adolescence
and a public health concern. Childhood depression is a key risk factor for later suicidality …