Synthetic cells revisited: Artificial cell construction using polymeric building blocks

V Maffeis, L Heuberger, A Nikoletić… - Advanced …, 2024 - Wiley Online Library
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …

[HTML][HTML] Enzyme cascade electrode reactions with nanomaterials and their applicability towards biosensor and biofuel cells

S Kalyana Sundaram, MM Hossain, M Rezki, K Ariga… - Biosensors, 2023 - mdpi.com
Nanomaterials, including carbon nanotubes, graphene oxide, metal–organic frameworks,
metal nanoparticles, and porous carbon, play a crucial role as efficient carriers to enhance …

Membrane and lumen-compartmentalized polymersomes for biocatalysis and cell mimics

Q Sun, J Shi, H Sun, Y Zhu, J Du - Biomacromolecules, 2023 - ACS Publications
Compartmentalization is a crucial feature of a natural cell, manifested in cell membrane and
inner lumen. Inspired by the cellular structure, multicompartment polymersomes (MCPs) …

Lipid vesicle-based molecular robots

Z Peng, S Iwabuchi, K Izumi, S Takiguchi, M Yamaji… - Lab on a Chip, 2024 - pubs.rsc.org
A molecular robot, which is a system comprised of one or more molecular machines and
computers, can execute sophisticated tasks in many fields that span from nanomedicine to …

Microfluidic Giant Polymer Vesicles Equipped with Biopores for High‐Throughput Screening of Bacteria

L Heuberger, D Messmer, EC Dos Santos… - Advanced …, 2024 - Wiley Online Library
Understanding the mechanisms of antibiotic resistance is critical for the development of new
therapeutics. Traditional methods for testing bacteria are often limited in their efficiency and …

Sono-Assembly of Polyphenol–Protein Capsules for Enhanced Biocatalytic Cascades

X Cui, Z Gao, K Zhao, N Wang, Q Yu… - Chemistry of …, 2024 - ACS Publications
We report a versatile approach for engineering protein capsules by harnessing the
ultrasonication-mediated assembly (sono-assembly) of protein-stabilized emulsions for …

Physically and Chemically Compartmentalized Polymersomes for Programmed Delivery and Biological Applications

Y Gao, C Gao, Y Fan, H Sun, J Du - Biomacromolecules, 2023 - ACS Publications
Multicompartment polymersomes (MCPs) refer to polymersomes that not only contain one
single compartment, either in the membrane or in the internal cavity, but also mimic the …

An Outer Membrane‐Inspired Polymer Coating Protects and Endows Escherichia coli with Novel Functionalities

A Belluati, I Harley, I Lieberwirth, N Bruns - Small, 2023 - Wiley Online Library
A bio‐inspired membrane made of Pluronic L‐121 is produced around Escherichia coli
thanks to the simple co‐extrusion of bacteria and polymer vesicles. The block copolymer …

Polymeric Giant Unilamellar Vesicles with Integrated DNA‐Origami Nanopores: An Efficient Platform for Tuning Bioreaction Dynamics Through Controlled Molecular …

R Cochereau, V Maffeis, EC Dos Santos… - Advanced Functional …, 2023 - Wiley Online Library
Giant unilamellar vesicles (GUVs) are microcompartments serving to confine reactions,
allow signaling pathways, or design synthetic cells. Polymer GUVs are composed of …

Glycooligomer-functionalized catalytic nanocompartments Co-loaded with enzymes support parallel reactions and promote cell internalization

M Korpidou, J Becker, S Tarvirdipour, IA Dinu… - …, 2024 - ACS Publications
A major shortcoming associated with the application of enzymes in drug synergism
originates from the lack of site-specific, multifunctional nanomedicine. This study introduces …