α-and β-Glucosidase inhibitors: chemical structure and biological activity

EB de Melo, A da Silveira Gomes, I Carvalho - Tetrahedron, 2006 - Elsevier
Glycoside trimming enzymes are crucially important in a broad range of metabolic pathways,
including glycoprotein and glycolipid processing and carbohydrate digestion in the intestinal …

The chemistry of the carbon–transition metal double and triple bond: Annual survey covering the year 2004

JW Herndon - Coordination chemistry reviews, 2006 - Elsevier
This is a review of papers published in the year 2004 that focus on the synthesis, reactivity,
or properties of compounds containing a carbon–transition metal double or triple bond.

The first synthesis of substituted azepanes mimicking monosaccharides: a new class of potent glycosidase inhibitors

H Li, Y Blériot, C Chantereau, JM Mallet… - Organic & …, 2004 - pubs.rsc.org
The synthesis of the first examples of seven-membered ring iminoalditols, molecules
displaying an extra hydroxymethyl substituent on their seven-membered ring compared to …

Synthesis and evaluation of eight-and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase …

JC Lee, S Francis, D Dutta, V Gupta… - The Journal of …, 2012 - ACS Publications
Eight-and four-membered analogues of N-butyldeoxynojirimycin (NB-DNJ), a reversible
male contraceptive in mice, were prepared and tested. A chiral pool approach was used for …

Asymmetric Remote Addition Reactions of Heterocycle‐Based Dearomative Dienamine or Trienamine Species to 1‐Azadienes: Application to Construct Chiral …

D Hu, Y Gao, X Song, W Du… - European Journal of …, 2020 - Wiley Online Library
The dearomative dienamines between a few five‐membered heteroaryl aldehydes and
chiral secondary amine catalysts underwent highly regio‐, chemo‐and stereoselective …

General synthesis and biological evaluation of α-1-C-substituted derivatives of fagomine (2-deoxynojirimycin-α-C-glycosides)

JY Goujon, D Gueyrard, P Compain, OR Martin… - Bioorganic & medicinal …, 2005 - Elsevier
A general synthesis of α-1-C-substituted derivatives of fagomine (2-deoxynojirimycin-α-C-
glycosides) by ring-opening reactions of an aziridine with various heteroatomic …

The Swern oxidation: Development of a high-temperature semicontinuous process

JR McConnell, JE Hitt, ED Daugs… - … Process Research & …, 2008 - ACS Publications
The Swern oxidation has been widely exploited for the oxidation of alcohols to their
respective carbonyl compounds. The cryogenic operating conditions (<− 60° C) employed …

Synthesis of spirocyclopropyl γ-lactams by tandem intramolecular azetidine ring-opening/closing cascade reaction: synthetic and mechanistic aspects

PA Nocquet, D Hazelard, P Compain - Tetrahedron, 2012 - Elsevier
The scope and limitations of a novel intramolecular azetidine ring-opening/closing cascade
reaction affording spirocyclopropyl γ-lactams from azetidines in high regio-and …

New 1-amino-1-deoxy-and 2-amino-2-deoxy-polyhydroxyazepanes: synthesis and inhibition of glycosidases

H Li, Y Blériot, JM Mallet, E Rodriguez-Garcia… - Tetrahedron …, 2005 - Elsevier
Eight new seven-membered ring iminoalditols, displaying an amino group and a
hydroxymethyl group on the ring, have been synthesized from d-arabinose via epoxidation …

Transition metals in organic synthesis: highlights for the year 2001

BCG Söderberg - Coordination chemistry reviews, 2003 - Elsevier
A review with 1663 references to transition-metal catalyzed or mediated reactions and
functional group preparations.