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Endometriosis: the role of neuroangiogenesis
Endometriosis is a common cause of pelvic pain and infertility, affecting∼ 10% of
reproductive-age women. Annual costs for medical and surgical care in the United States …
reproductive-age women. Annual costs for medical and surgical care in the United States …
GDNF and the RET receptor in cancer: new insights and therapeutic potential
LM Mulligan - Frontiers in physiology, 2019 - frontiersin.org
The Glial cell line-derived neurotrophic Family Ligands (GFL) are soluble neurotrophic
factors that are required for development of multiple human tissues, but which are also …
factors that are required for development of multiple human tissues, but which are also …
Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid
Human glioblastoma multiforme (hGBM) is the most common, aggressive, and deadly form
of brain cancer. A major obstacle to understanding the impact of extracellular cues on …
of brain cancer. A major obstacle to understanding the impact of extracellular cues on …
Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy
Three‐dimensional tissue engineered constructs provide a platform to examine how the
local extracellular matrix (ECM) contributes to the malignancy of cancers such as human …
local extracellular matrix (ECM) contributes to the malignancy of cancers such as human …
The role of miRNA-223 in cancer: Function, diagnosis and therapy
Y Gao, L Lin, T Li, J Yang, Y Wei - Gene, 2017 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small, non-coding RNAs with the capacity
to regulate gene expression post-transcriptionally. miRNAs appear to hold promise of …
to regulate gene expression post-transcriptionally. miRNAs appear to hold promise of …
RET in breast cancer: functional and therapeutic implications
Recent studies demonstrate that the receptor tyrosine kinase RET is overexpressed in a
subset of ER-positive breast cancers and that crosstalk between RET and ER is important in …
subset of ER-positive breast cancers and that crosstalk between RET and ER is important in …
Tumor expression of human growth hormone and human prolactin predict a worse survival outcome in patients with mammary or endometrial carcinoma
ZS Wu, K Yang, Y Wan, PX Qian… - The Journal of …, 2011 - academic.oup.com
Context: Evidence suggests that human GH (hGH) and human prolactin (hPRL) possess an
autocrine or paracrine oncogenic role in mammary and endometrial carcinoma. However …
autocrine or paracrine oncogenic role in mammary and endometrial carcinoma. However …
Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma
Introduction Recurrence or early metastasis remains the predominant cause of mortality in
patients with estrogen receptor positive (ER+) mammary carcinoma (MC). However, the …
patients with estrogen receptor positive (ER+) mammary carcinoma (MC). However, the …
Targeting rearranged during transfection in cancer: A perspective on small-molecule inhibitors and their clinical development
Rearranged during transfection (RET) is a receptor tyrosine kinase essential for the normal
development and maturation of a diverse range of tissues. Aberrant RET signaling in …
development and maturation of a diverse range of tissues. Aberrant RET signaling in …
[HTML][HTML] The GDNF family: a role in cancer?
The glial cell line–derived neurotrophic factor (GDNF) family of ligands (GFLs) comprising of
GDNF, neurturin, artemin, and persephin plays an important role in the development and …
GDNF, neurturin, artemin, and persephin plays an important role in the development and …