Endometriosis: the role of neuroangiogenesis

A Asante, RN Taylor - Annual review of physiology, 2011 - annualreviews.org
Endometriosis is a common cause of pelvic pain and infertility, affecting∼ 10% of
reproductive-age women. Annual costs for medical and surgical care in the United States …

GDNF and the RET receptor in cancer: new insights and therapeutic potential

LM Mulligan - Frontiers in physiology, 2019 - frontiersin.org
The Glial cell line-derived neurotrophic Family Ligands (GFL) are soluble neurotrophic
factors that are required for development of multiple human tissues, but which are also …

Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid

S Pedron, E Becka, BAC Harley - Biomaterials, 2013 - Elsevier
Human glioblastoma multiforme (hGBM) is the most common, aggressive, and deadly form
of brain cancer. A major obstacle to understanding the impact of extracellular cues on …

Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy

S Pedron, BAC Harley - … Materials Research Part A: An Official …, 2013 - Wiley Online Library
Three‐dimensional tissue engineered constructs provide a platform to examine how the
local extracellular matrix (ECM) contributes to the malignancy of cancers such as human …

The role of miRNA-223 in cancer: Function, diagnosis and therapy

Y Gao, L Lin, T Li, J Yang, Y Wei - Gene, 2017 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small, non-coding RNAs with the capacity
to regulate gene expression post-transcriptionally. miRNAs appear to hold promise of …

RET in breast cancer: functional and therapeutic implications

A Morandi, I Plaza-Menacho, CM Isacke - Trends in molecular medicine, 2011 - cell.com
Recent studies demonstrate that the receptor tyrosine kinase RET is overexpressed in a
subset of ER-positive breast cancers and that crosstalk between RET and ER is important in …

Tumor expression of human growth hormone and human prolactin predict a worse survival outcome in patients with mammary or endometrial carcinoma

ZS Wu, K Yang, Y Wan, PX Qian… - The Journal of …, 2011 - academic.oup.com
Context: Evidence suggests that human GH (hGH) and human prolactin (hPRL) possess an
autocrine or paracrine oncogenic role in mammary and endometrial carcinoma. However …

Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma

V Pandey, ZS Wu, M Zhang, R Li, J Zhang, T Zhu… - Breast Cancer …, 2014 - Springer
Introduction Recurrence or early metastasis remains the predominant cause of mortality in
patients with estrogen receptor positive (ER+) mammary carcinoma (MC). However, the …

Targeting rearranged during transfection in cancer: A perspective on small-molecule inhibitors and their clinical development

D Saha, KR Ryan, NR Lakkaniga… - Journal of medicinal …, 2021 - ACS Publications
Rearranged during transfection (RET) is a receptor tyrosine kinase essential for the normal
development and maturation of a diverse range of tissues. Aberrant RET signaling in …

[HTML][HTML] The GDNF family: a role in cancer?

GC Fielder, TWS Yang, M Razdan, Y Li, J Lu, JK Perry… - Neoplasia, 2018 - Elsevier
The glial cell line–derived neurotrophic factor (GDNF) family of ligands (GFLs) comprising of
GDNF, neurturin, artemin, and persephin plays an important role in the development and …