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Toward an understanding of the correlates of protective immunity to HIV infection
Considerable progress has been made recently in understanding the genetic, immunologic,
and virologic factors in human immunodeficiency virus (HIV)-infected individuals who either …
and virologic factors in human immunodeficiency virus (HIV)-infected individuals who either …
Transition between stochastic evolution and deterministic evolution in the presence of selection: general theory and application to virology
We present here a self-contained analytic review of the role of stochastic factors acting on a
virus population. We develop a simple one-locus, two-allele model of a haploid population …
virus population. We develop a simple one-locus, two-allele model of a haploid population …
Population dynamics of immune responses to persistent viruses
MA Nowak, CRM Bangham - Science, 1996 - science.org
Mathematical models, which are based on a firm understanding of biological interactions,
can provide nonintuitive insights into the dynamics of host responses to infectious agents …
can provide nonintuitive insights into the dynamics of host responses to infectious agents …
Consistent viral evolutionary changes associated with the progression of human immunodeficiency virus type 1 infection
RAJ Shankarappa, JB Margolick, SJ Gange… - Journal of …, 1999 - journals.asm.org
To understand the high variability of the asymptomatic interval between primary human
immunodeficiency virus type 1 (HIV-1) infection and the development of AIDS, we studied …
immunodeficiency virus type 1 (HIV-1) infection and the development of AIDS, we studied …
[책][B] Integration of modern taxonomic methods for Penicillium and Aspergillus classification
Many species of penicillium and aspergillus are important in biotechnology, food, medicine,
biodeterioration and other applied fields, so a practical and stable taxonomy is of vital …
biodeterioration and other applied fields, so a practical and stable taxonomy is of vital …
Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy
We examined the pathogenic significance of the latent viral reservoir in the resting CD4+ T
cell compartment of HIV-1-infected individuals as well as its involvement in the rebound of …
cell compartment of HIV-1-infected individuals as well as its involvement in the rebound of …
Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection
The rate of progression to disease varies considerably among individuals infected with
human immunodeficiency virus-type 1 (HIV-1). Analyses of semiannual blood samples …
human immunodeficiency virus-type 1 (HIV-1). Analyses of semiannual blood samples …
Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection
M Altfeld, ES Rosenberg, R Shankarappa… - Journal of Experimental …, 2001 - rupress.org
Immune responses induced during the early stages of chronic viral infections are thought to
influence disease outcome. Using HIV as a model, we examined virus-specific cytotoxic T …
influence disease outcome. Using HIV as a model, we examined virus-specific cytotoxic T …
Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual …
T Zhu, N Wang, A Carr, DS Nam… - Journal of …, 1996 - journals.asm.org
To explore the mechanism of sexual transmission of human immunodeficiency virus type 1
(HIV-1), we compared HIV-1 gp120 sequences in longitudinal samples from five acute …
(HIV-1), we compared HIV-1 gp120 sequences in longitudinal samples from five acute …