Secondary bile acids and short chain fatty acids in the colon: a focus on colonic microbiome, cell proliferation, inflammation, and cancer

H Zeng, S Umar, B Rust, D Lazarova… - International journal of …, 2019 - mdpi.com
Secondary bile acids (BAs) and short chain fatty acids (SCFAs), two major types of bacterial
metabolites in the colon, cause opposing effects on colonic inflammation at chronically high …

Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

G Cuevas-Ramos, CR Petit, I Marcq… - Proceedings of the …, 2010 - National Acad Sciences
Escherichia coli is a normal inhabitant of the human gut. However, E. coli strains of
phylogenetic group B2 harbor a genomic island called “pks” that codes for the production of …

High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

E Buc, D Dubois, P Sauvanet, J Raisch, J Delmas… - PloS one, 2013 - journals.plos.org
Some Escherichia coli strains produce toxins designated cyclomodulins (CMs) which
interfere with the eukaryotic cell cycle of host cells, suggesting a possible link between these …

Structure elucidation of colibactin and its DNA cross-links

M Xue, C Struve, CC Roe, M Stegger, SG Stahlhut, DS Hansen… - MBio, 2015 - Am Soc Microbiol
Highly invasive, community-acquired Klebsiella pneumoniae infections have recently
emerged, resulting in pyogenic liver abscesses. These infections are caused by …

Distinguishing pathovars from nonpathovars: Escherichia coli

LW Riley - Microbiology spectrum, 2020 - Am Soc Microbiol
Escherichia coli is one of the most well-adapted and pathogenically versatile bacterial
organisms. It causes a variety of human infections, including gastrointestinal illnesses and …

Type VI Secretion System in Pathogenic Escherichia coli: Structure, Role in Virulence, and Acquisition

F Navarro-Garcia, F Ruiz-Perez, Á Cataldi… - Frontiers in …, 2019 - frontiersin.org
Bacterial pathogens utilize a myriad of mechanisms to invade mammalian hosts, damage
tissue sites, and evade the immune system. One essential strategy of Gram-negative …