2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19

D Farge, C Frere, JM Connors, AA Khorana… - The Lancet …, 2022 - thelancet.com
Summary The International Initiative on Thrombosis and Cancer is an independent
academic working group of experts aimed at establishing global consensus for the treatment …

Cancer-associated venous thromboembolism

AA Khorana, N Mackman, A Falanga… - Nature reviews Disease …, 2022 - nature.com
Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Pharmacology of heparin and related drugs: an update

J Hogwood, B Mulloy, R Lever, E Gray… - Pharmacological reviews, 2023 - Elsevier
Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Factor XI inhibitors: cardiovascular perspectives

R De Caterina, D Prisco… - European Heart …, 2023 - academic.oup.com
Anticoagulants are the cornerstone for prevention and treatment of thrombosis but are not
completely effective, and concerns about the risk of bleeding continue to limit their uptake …

Estimating bleeding risk in patients with cancer-associated thrombosis: evaluation of existing risk scores and development of a new risk score

MA De Winter, JAN Dorresteijn… - Thrombosis and …, 2022 - thieme-connect.com
Background Bleeding risk is highly relevant for treatment decisions in cancer-associated
thrombosis (CAT). Several risk scores exist, but have never been validated in patients with …

[HTML][HTML] Extended anticoagulation treatment for cancer‐associated thrombosis—Rates of recurrence and bleeding beyond 6 months: A systematic review

F Moik, M Colling, I Mahé, L Jara‐Palomares… - Journal of Thrombosis …, 2022 - Elsevier
Background Patients with cancer‐associated venous thromboembolism (VTE) are
recommended to receive treatment with therapeutic anticoagulation for at least 3–6 months …

Venous and arterial thromboembolism in patients with cancer treated with targeted anti-cancer therapies

F Moik, C Ay - Thrombosis Research, 2022 - Elsevier
Patients with cancer have an increased risk of venous-and arterial thromboembolism
(VTE/ATE). Anti-cancer treatments including surgery, radiotherapy, and certain …

Thrombosis in multiple myeloma: risk stratification, antithrombotic prophylaxis, and management of acute events. A consensus-based position paper from an ad hoc …

V De Stefano, A Larocca, M Carpenedo… - …, 2022 - pmc.ncbi.nlm.nih.gov
The introduction of new therapeutic agents for multiple myeloma (MM), including
proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies, has improved …

Unanswered questions in cancer‐associated thrombosis

KM Sanfilippo, F Moik, M Candeloro… - British Journal of …, 2022 - Wiley Online Library
Cancer‐associated venous thromboembolism (VTE) is a leading cause of morbidity and
mortality in patients with cancer. Treatment of cancer‐associated VTE comes with a …

Treatment of cancer-associated thrombosis: recent advances, unmet needs, and future direction

TF Wang, AA Khorana, G Agnelli, D Bloomfield… - The …, 2023 - academic.oup.com
Cancer-associated thrombosis, with the incidence rising over the years, is associated with
significant morbidity and mortality in patients with cancer. Recent advances in the treatment …