Targeting chronic liver diseases: Molecular markers, drug delivery strategies and future perspectives

J Unagolla, S Das, R Flanagan, M Oehler… - International Journal of …, 2024 - Elsevier
Chronic liver inflammation, a pervasive global health issue, results in millions of annual
deaths due to its progression from fibrosis to the more severe forms of cirrhosis and …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Carbohydrates used in polymeric systems for drug delivery: from structures to applications

X Di, X Liang, C Shen, Y Pei, B Wu, Z He - Pharmaceutics, 2022 - mdpi.com
Carbohydrates, one of the most important compounds in living organisms, perform
numerous roles, including those associated with the extracellular matrix, energy-related …

Apocynin-loaded PLGA nanomedicine tailored with galactosylated chitosan intrigue asialoglycoprotein receptor in hepatic carcinoma: prospective targeted therapy

HM Anter, RM Aman, DIA Othman, KM Elamin… - International Journal of …, 2023 - Elsevier
Nature serves as a priceless source for phytomedicines to treat different types of cancer,
including hepatocellular carcinoma (HCC). Apocynin (APO), an anti-cancer phytomedicine …

Propitious maneuvering for delivery of the phytopharmaceutical “apocynin” to induced fulminant hepatitis in BALB/c mice: In vitro and in vivo assessments

HM Anter, RM Aman, AA Shaaban, IIA Hashim… - International Journal of …, 2022 - Elsevier
Apocynin (APO), a specific nicotinamide adenine dinucleotide phosphate-oxidase (NADPH-
oxidase, NOX) inhibitor, has recently emerged as a bioactive phytochemical with eminent …

Anticancer therapeutic potential of phosphorylated galactosylated chitosan against N-nitrosodiethyl amine-induced hepatocarcinogenesis

U Anushree, S Shetty, SD Kulkarni, H Kumar… - Archives of Biochemistry …, 2022 - Elsevier
Chitosan is a natural polyfunctional polymer that can be modified to achieve compounds
with tailored properties for targeting and treating different cancers. In this study, we report the …

Glycosylated nanoplatforms: From glycosylation strategies to implications and opportunities for cancer theranostics

I Zare, SZH Kiadeh, A Varol, TÖ Varol, M Varol… - Journal of Controlled …, 2024 - Elsevier
Glycosylated nanoplatforms have emerged as promising tools in the field of cancer
theranostics, integrating both therapeutic and diagnostic functionalities. These nanoscale …

[HTML][HTML] Fabrication and evaluation of mannose decorated curcumin loaded nanostructured lipid carriers for hepatocyte targeting: In vivo hepatoprotective activity in …

MK Gupta, V Sansare, B Shrivastava, S Jadhav… - Current Research in …, 2022 - Elsevier
Curcumin is a well-recognized antioxidant phytoactive isolated from the rhizomes of
Curcuma longa. Numerous landmark investigations have proved the antioxidant and …

Characterization and therapeutic effect of a pH stimuli responsive polymeric nanoformulation for controlled drug release

MV Cano-Cortes, JA Laz-Ruiz, JJ Diaz-Mochon… - Polymers, 2020 - mdpi.com
Despite the large number of polymeric nanodelivery systems that have been recently
developed, there is still room for improvement in terms of therapeutic efficiency. Most …

Development of a Polymeric Pharmacological Nanocarrier System as a Potential Therapy for Spinocerebellar Ataxia Type 7

FV Borbolla-Jiménez, IA García-Aguirre… - Cells, 2023 - mdpi.com
Spinocerebellar ataxia type 7 (SCA7) is an autosomal-dominant inherited disease
characterized by progressive ataxia and retinal degeneration. SCA7 belongs to a group of …