Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Biomarkers: Promising and valuable tools towards diagnosis, prognosis and treatment of Covid-19 and other diseases

A Bodaghi, N Fattahi, A Ramazani - Heliyon, 2023 - cell.com
The use of biomarkers as early warning systems in the evaluation of disease risk has
increased markedly in the last decade. Biomarkers are indicators of typical biological …

Surface-functionalized gold and silver nanoparticles for colorimetric and fluorescent sensing of metal ions and biomolecules

S Chatterjee, XY Lou, F Liang, YW Yang - Coordination Chemistry Reviews, 2022 - Elsevier
Surface-functionalized gold and silver nanoparticles, AuNPs and AgNPs for short, prepared
via the modification of organic chelating motifs by covalent or non-covalent bonds, represent …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person

L Koklesova, A Mazurakova, M Samec, K Biringer… - EPMA Journal, 2021 - Springer
Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …

Smart molecular designs and applications of activatable organic photosensitizers

E Nestoros, A Sharma, E Kim, JS Kim… - Nature Reviews …, 2024 - nature.com
Photodynamic therapy (PDT)—which combines light, oxygen and photosensitizers (PS) to
generate reactive oxygen species—has emerged as an effective approach for targeted …

Parkinson's disease risk and hyperhomocysteinemia: the possible link

HM Al-Kuraishy, AI Al-Gareeb, YHA Elewa… - Cellular and Molecular …, 2023 - Springer
Parkinson's disease (PD) is one of the most common degenerative brain disorders caused
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …

Oxidase-like Nanozyme Activity of Manganese Metal–Organic Framework Nanosheets for Colorimetric and Fluorescence Sensing of l-Cysteine

AK Singh, K Bijalwan, N Kaushal… - ACS Applied Nano …, 2023 - ACS Publications
The utilization of ultrathin Mn-metal–organic framework (Mn-UMOF) nanosheets for oxidase-
like nanozyme activity has been demonstrated. The Mn-UMOF exhibited superior nanozyme …

Targeted cysteine and glutathione detection in extra/intracellular systems by copper-based fluorescent imaging probes

T Nagendraraj, SV Priya, J Annaraj… - Coordination Chemistry …, 2023 - Elsevier
The three primary biothiols are cysteine (Cys), glutathione (GSH), and homocysteine (Hcy)
which plays key functions in a variety of biological processes. Intracellular and extracellular …

One-carbon metabolism shapes T cell immunity in cancer

Y Qiu, E **e, H Xu, H Cheng, G Li - Trends in Endocrinology & Metabolism, 2024 - cell.com
Abstract One-carbon metabolism (1CM), comprising folate metabolism and methionine
metabolism, serves as an important mechanism for cellular energy provision and the …