Cartilage tissue engineering is emerging as a technique for the regeneration of cartilage
tissue damaged due to disease or trauma. Since cartilage lacks regenerative capabilities, it …

This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …

Cartilage tissue presents low self‐repair capability and lesions often undergo irreversible
progression. Structures obtained by tissue engineering, such as those based in extrusion …

Tissue Engineering (TE) aims to create biological substitutes to repair or replace failing
organs or tissues due to trauma or ageing. One of the more promising approaches in TE is to …

Articular cartilage damage is a persistent and increasing problem with the aging population,
and treatments to achieve biological repair or restoration remain a challenge. Cartilage …

The lack of practicable nonlinear elastic contact models frequently compels the
inappropriate use of Hertzian models in analyzing indentation data and likely contributes to …

Tissue architecture is intimately linked with its functions, and loss of tissue organization is
often associated with pathologies. The intricate depth-dependent extracellular matrix (ECM) …

OBJECTIVE: During postnatal development, mammalian articular cartilage acts as a surface
growth plate for the underlying epiphyseal bone. Concomitantly, it undergoes a fundamental …

Matching tissue engineering scaffold modulus to that of native tissue is highly desirable.
Effective scaffold modulus can be altered through changes in base material modulus and/or …