Placental function in maternal obesity

AC Kelly, TL Powell, T Jansson - Clinical Science, 2020 - portlandpress.com
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …

Why primate models matter

KA Phillips, KL Bales, JP Capitanio… - American journal of …, 2014 - Wiley Online Library
Research involving nonhuman primates (NHPs) has played a vital role in many of the
medical and scientific advances of the past century. NHPs are used because of their …

A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration

C Salomon, MJ Torres, M Kobayashi… - PloS one, 2014 - journals.plos.org
Studies completed to date provide persuasive evidence that placental cell-derived
exosomes play a significant role in intercellular communication pathways that potentially …

Child health, developmental plasticity, and epigenetic programming

Z Hochberg, R Feil, M Constancia, M Fraga… - Endocrine …, 2011 - academic.oup.com
Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Racial/ethnic disparities in obstetric outcomes and care: prevalence and determinants

AS Bryant, A Worjoloh, AB Caughey… - American journal of …, 2010 - Elsevier
Wide disparities in obstetric outcomes exist between women of different race/ethnicities. The
prevalence of preterm birth, fetal growth restriction, fetal demise, maternal mortality, and …

Early-life programming of later-life brain and behavior: a critical role for the immune system

SD Bilbo, JM Schwarz - Frontiers in behavioral neuroscience, 2009 - frontiersin.org
The immune system is well characterized for its critical role in host defense. Far beyond this
limited role however, there is mounting evidence for the vital role the immune system plays …

[PDF][PDF] Focus on obesity: Impact of maternal obesity on offspring obesity and cardiometabolic disease risk

AJ Drake, RM Reynolds - Reproduction, 2010 - scholar.archive.org
The prevalence of obesity among pregnant women is increasing. In addition to the short-
term complications of obesity during pregnancy in both mother and child, it is now …

Obesity in pregnancy: implications for the mother and lifelong health of the child. A consensus statement

L Poston, LF Harthoorn, EM Van Der Beek - Pediatric research, 2011 - nature.com
Obesity among pregnant women is becoming one of the most important women's health
issues. Obesity is associated with increased risk of almost all pregnancy complications …

Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet

GJ Howie, DM Sloboda, T Kamal… - The Journal of …, 2009 - Wiley Online Library
Significant alterations in maternal nutrition may induce long‐term metabolic consequences
in offspring, in particular obesity and leptin and insulin resistance. Although maternal …

Changing epidemiology of colorectal cancer—birth cohort effects and emerging risk factors

CC Murphy, TA Zaki - Nature reviews Gastroenterology & hepatology, 2024 - nature.com
Incidence and mortality of colorectal cancer (CRC) are increasing worldwide, suggesting
broad changes in the epidemiology of CRC. In this Review, we discuss the changes that are …