Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

Classic psychedelics produce altered states of consciousness that individuals often interpret
as meaningful experiences. Across a number of human studies, when the participant-rated …

Importance Major depressive disorder (MDD) is a substantial public health burden, but
current treatments have limited effectiveness and adherence. Recent evidence suggests that …

Objective: The authors provide an evidenced-based summary of the literature on the clinical
application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and …

The purpose of this paper is to provide an integrative review and offer novel insights
regarding human research with classic psychedelics (classic hallucinogens), which are …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely
in controlled conditions, and can cause lasting psychological benefits with one or two …

No contemporary unifying framework has been provided for the study of non-ordinary states
of consciousness (NSCs) despite increased interest in hypnosis, meditation, and …