Platelet-rich plasma (PRP): methodological aspects and clinical applications

LF Marques, T Stessuk, ICC Camargo, N Sabeh Junior… - Platelets, 2015 - Taylor & Francis
The clinical use of platelet-rich plasma (PRP) is based on the increase in the concentration
of growth factors and in the secretion of proteins which are able to maximize the healing …

New and emerging strategies in platelet‐rich plasma application in musculoskeletal regenerative procedures: General overview on still open questions and outlook

F Salamanna, F Veronesi, M Maglio… - BioMed Research …, 2015 - Wiley Online Library
Despite its pervasive use, the clinical efficacy of platelet‐rich plasma (PRP) therapy and the
different mechanisms of action have yet to be established. This overview of the literature is …

Platelet-rich plasma: a milieu of bioactive factors

SG Boswell, BJ Cole, EA Sundman, V Karas… - Arthroscopy: The journal …, 2012 - Elsevier
Platelet concentrates such as platelet-rich plasma (PRP) have gained popularity in sports
medicine and orthopaedics to promote accelerated physiologic healing and return to …

Platelet-rich plasma stimulates cell proliferation and enhances matrix gene expression and synthesis in tenocytes from human rotator cuff tendons with degenerative …

CH Jo, JE Kim, KS Yoon, S Shin - The American journal of …, 2012 - journals.sagepub.com
Background: Platelet-rich plasma (PRP) contains various growth factors and appears to
have a potential to promote tendon healing, but evidence is lacking regarding its effect on …

Increasing platelet concentrations in leukocyte-reduced platelet-rich plasma decrease collagen gene synthesis in tendons

SG Boswell, LV Schnabel… - … American journal of …, 2014 - journals.sagepub.com
Background: Platelet-rich plasma (PRP) is used for the treatment of tendinopathy. There are
numerous PRP preparations, and the optimal combination of platelets and leukocytes is not …

The positive effects of different platelet-rich plasma methods on human muscle, bone, and tendon cells

AD Mazzocca, MBR McCarthy… - … American journal of …, 2012 - journals.sagepub.com
Background: Clinical application of platelet-rich plasma (PRP) in the realm of orthopaedic
sports medicine has yielded variable results. Differences in separation methods and …

Antimicrobial activity of platelet‐rich plasma and other plasma preparations against periodontal pathogens

LC Yang, SW Hu, M Yan, JJ Yang… - Journal of …, 2015 - Wiley Online Library
Background: In addition to releasing a pool of growth factors during activation, platelets have
many features that indicate their role in the anti‐infective host defense. The antimicrobial …

Homologous platelet-rich plasma for the treatment of knee osteoarthritis in selected elderly patients: an open-label, uncontrolled, pilot study

C Bottegoni, L Dei Giudici, S Salvemini… - Therapeutic …, 2016 - journals.sagepub.com
Objective: The objective of this study was to evaluate the safety and the effect of platelet-rich
plasma (PRP) intra-articular injections obtained from blood donors (homologous PRP) on …

Fixation of platelet-rich plasma and fibrin gels on knee cartilage defects after microfracture with arthroscopy

M Wang, W Gao - International Orthopaedics, 2022 - Springer
Purpose An investigation of arthroscopic surgery combined with coverage of the
microfractured wound surface with platelet-rich plasma (PRP) and fibrin gels (FG) to treat …

Biological activity of a standardized freeze-dried platelet derivative to be used as cell culture medium supplement

A Muraglia, C Ottonello, R Spanò, B Dozin, P Strada… - Platelets, 2014 - Taylor & Francis
Serum of animal origin and in particular fetal bovine serum is the most commonly utilized
cell culture medium additive for in vitro cell growth and differentiation. However, several …