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Targeting of hepatic macrophages by therapeutic nanoparticles
Hepatic macrophage populations include different types of cells with plastic properties that
can differentiate into diverse phenotypes to modulate their properties in response to different …
can differentiate into diverse phenotypes to modulate their properties in response to different …
[HTML][HTML] Plant-derived nanovesicles: Further exploration of biomedical function and application potential
A Li, D Li, Y Gu, R Liu, X Tang, Y Zhao, F Qi… - … Pharmaceutica Sinica B, 2023 - Elsevier
Extracellular vesicles (EVs) are phospholipid bilayer vesicles actively secreted by cells, that
contain a variety of functional nucleic acids, proteins, and lipids, and are important mediums …
contain a variety of functional nucleic acids, proteins, and lipids, and are important mediums …
Internalization of garlic-derived nanovesicles on liver cells is triggered by interaction with CD98
The mechanism of how plant-derived nanovesicles are uptaken by cells remains unknown.
In this study, the garlic-derived nanovesicles (GDVs) were isolated and digested with trypsin …
In this study, the garlic-derived nanovesicles (GDVs) were isolated and digested with trypsin …
[HTML][HTML] Potential and applications of nanocarriers for efficient delivery of biopharmaceuticals
During the past two decades, the clinical use of biopharmaceutical products has markedly
increased because of their obvious advantages over conventional small-molecule drug …
increased because of their obvious advantages over conventional small-molecule drug …
The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State‐of‐the‐Art Review
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can lead to
end‐stage liver disease needing a liver transplant. Many pharmacological approaches are …
end‐stage liver disease needing a liver transplant. Many pharmacological approaches are …
Factors affecting the clearance and biodistribution of polymeric nanoparticles
Nanoparticles are promising drug delivery for various therapeutic applications.
Pharmacokinetics is important to study the in vivo fate of nanoparticles. Biodistribution and …
Pharmacokinetics is important to study the in vivo fate of nanoparticles. Biodistribution and …
Delivery of microRNA-33 antagomirs by mesoporous silica nanoparticles to ameliorate lipid metabolic disorders
Lipid metabolic disorders have become a major global public health concern. Fatty liver and
dyslipidemia are major manifestations of these disorders. Recently, MicroRNA-33 (miR-33) …
dyslipidemia are major manifestations of these disorders. Recently, MicroRNA-33 (miR-33) …
[HTML][HTML] Digoxin mitigates diethylnitrosamine-induced acute liver injury in mice via limiting production of inflammatory mediators
The cardiotonic digoxin has been recently shown to possess an anti-inflammatory potential
in numerous metabolic and inflammatory disorders. However, data about digoxin's impact in …
in numerous metabolic and inflammatory disorders. However, data about digoxin's impact in …
Doxorubicin Intracellular Release Via External UV Irradiation of Dextran-g-poly(o-nitrobenzyl acrylate) Photosensitive Nanoparticles
M El Founi, H Laroui, BSB Canup… - ACS Applied Bio …, 2021 - ACS Publications
In the present study, innovative doxorubicin-loaded nanoparticles (NPs) made of a
photosensitive poly (o-nitrobenzyl acrylate)(PNBA) hydrophobic matrix and an hydrophilic …
photosensitive poly (o-nitrobenzyl acrylate)(PNBA) hydrophobic matrix and an hydrophilic …
Nano-drug delivery systems (NDDS) in metabolic dysfunction-associated steatotic liver disease (MASLD): current status, prospects and challenges
Y Yang, X Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
About one-third of the global population suffers from metabolic dysfunction-associated
steatotic liver disease (MASLD), but specific treatments for MASLD have long been lacking …
steatotic liver disease (MASLD), but specific treatments for MASLD have long been lacking …