Detergents are widely used for membrane protein solubilization, purification, and structural
analysis. Over the past two decades, much effort has been made to design novel detergents …

Detergents are amphiphilic molecules that serve as enabling steps for today's world
applications. The increasing diversity of the detergentome is key to applications enabled by …

Laurylmaltose neopentylglycol (LMNG) bears two linked hydrophobic chains of equal length
and two hydrophilic maltoside groups. It arouses a strong interest in the field of membrane …

Membrane proteins are of biological and pharmaceutical significance. However, their
structural study is extremely challenging mainly due to the fact that only a small number of …

Detergents are essential tools for functional and structural studies of membrane proteins.
However, conventional detergents are limited in their scope and utility, particularly for …

Integral membrane proteins are amphipathic molecules crucial for all cellular life. The
structural study of these macromolecules starts with protein extraction from the native …

Membrane proteins play essential roles in a number of biological processes, and their
structures are important in elucidating such processes at the molecular level and also for …

High-resolution membrane protein structures are essential for a fundamental understanding
of the molecular basis of diverse cellular processes and for drug discovery. Detergents are …

Maintaining protein stability in an aqueous solution is a prerequisite for protein structural
and functional studies, but conventional detergents have increasingly showed limited ability …

Mammalian F-ATP synthase is central to mitochondrial bioenergetics and is present in the
inner mitochondrial membrane in a dynamic oligomeric state of higher oligomers, tetramers …