Architecture of the subthalamic nucleus

AA Prasad, Å Wallén-Mackenzie - Communications Biology, 2024 - nature.com
The subthalamic nucleus (STN) is a major neuromodulation target for the alleviation of
neurological and neuropsychiatric symptoms using deep brain stimulation (DBS). STN-DBS …

Evolving characterization of the human hyperdirect pathway

CS Bingham, MV Petersen, M Parent… - Brain Structure and …, 2023 - Springer
The hyperdirect pathway (HDP) represents the main glutamatergic input to the subthalamic
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …

A role for the subthalamic nucleus in aversive learning

GP Serra, A Guillaumin, B Vlcek, L Delgado-Zabalza… - Cell Reports, 2023 - cell.com
The subthalamic nucleus (STN) is critical for behavioral control; its dysregulation
consequently correlated with neurological and neuropsychiatric disorders, including …

[HTML][HTML] Topographic connectivity and cellular profiling reveal detailed input pathways and functionally distinct cell types in the subthalamic nucleus

H Jeon, H Lee, DH Kwon, J Kim, K Tanaka-Yamamoto… - Cell reports, 2022 - cell.com
The subthalamic nucleus (STN) controls psychomotor activity and is an efficient therapeutic
deep brain stimulation target in individuals with Parkinson's disease. Despite evidence …

[HTML][HTML] Exploring the benefits of virtual reality-assisted therapy following cognitive-behavioral therapy for auditory hallucinations in patients with treatment-resistant …

L Dellazizzo, S Potvin, K Phraxayavong… - Journal of Clinical …, 2020 - mdpi.com
Background: Combining cognitive behavioral therapy (CBT) for psychosis with another
psychosocial intervention comprising virtual reality (VR)-assisted therapy (VRT) may …

Topography and distribution of adenosine A2A and dopamine D2 receptors in the human Subthalamic Nucleus

A Emmi, A Antonini, M Sandre, A Baldo… - Frontiers in …, 2022 - frontiersin.org
The human Subthalamic Nucleus (STh) is a diencephalic lens-shaped structure located
ventrally to the thalamus and functionally implicated in the basal ganglia circuits. Despite …

Mixed methodology in human brain research: integrating MRI and histology

A Alkemade, R Großmann, PL Bazin… - Brain Structure and …, 2023 - Springer
Postmortem magnetic resonance imaging (MRI) can provide a bridge between histological
observations and the in vivo anatomy of the human brain. Approaches aimed at the co …

[HTML][HTML] Functional segregation and integration within the human subthalamic nucleus from a micro-and meso-level perspective

BCM van Wijk, A Alkemade, BU Forstmann - Cortex, 2020 - Elsevier
The subthalamic nucleus (STN) is a core basal ganglia structure involved in the control of
motor, cognitive, motivational and affective functions. The (challenged) tripartite subdivision …

Single unit and beta oscillatory activities in subthalamic nucleus are modulated during visual choice preference

TM Al‐Ozzi, LF Botero-Posada… - European Journal of …, 2021 - Wiley Online Library
Parkinson's disease is a neurodegenerative disease affecting the supply of dopamine to
basal ganglia nuclei, leading to pathological beta band (13–35 Hz) oscillations in the …

Neurotransmitter and receptor systems in the subthalamic nucleus

A Emmi, M Campagnolo, E Stocco, M Carecchio… - Brain Structure and …, 2023 - Springer
Abstract The Subthalamic Nucleus (STh) is a lens-shaped subcortical structure located
ventrally to the thalamus, that despite being embryologically derived from the diencephalon …