Mesenchymal stem cell-derived extracellular vesicles in tendon and ligament repair—A systematic review of in vivo studies

V Lu, M Tennyson, J Zhang, W Khan - Cells, 2021 - mdpi.com
Tendon and ligament injury poses an increasingly large burden to society. This systematic
review explores whether mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) …

Allogenic synovia-derived mesenchymal stem cells for treatment of equine tendinopathies and desmopathies—Proof of concept

I Leal Reis, B Lopes, P Sousa, AC Sousa… - Animals, 2023 - mdpi.com
Simple Summary Horses are high-level athletic athletes prone to musculoskeletal injuries.
Tendon/ligament injuries are the most frequent types of injuries which that are very difficult to …

Batch effects during human bone marrow stromal cell propagation prevail donor variation and culture duration: impact on genotype, phenotype and function

G Brachtl, R Poupardin, S Hochmann, A Raninger… - Cells, 2022 - mdpi.com
Donor variation is a prominent critical issue limiting the applicability of cell-based therapies.
We hypothesized that batch effects during propagation of bone marrow stromal cells …

Mild synovitis impairs chondrogenic joint environment

S Paudel, T Feltham, L Manandhar, Y Guo… - Cells Tissues …, 2024 - karger.com
The impact of mild synovitis on the chondrogenic environment in the joint pertaining to
cartilage repair is often neglected. In this study, 21 synovial samples were collected from foot …

Cryopreserved allogeneic bone marrow mesenchymal stem cells show better osteochondral defect repair potential than adipose tissue mesenchymal stem cells

MB Gugjoo, ER Dar, F Farooq, SM Ahmad… - Current Research in …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) due to their characteristic properties have a potential to
treat osteoarthritis, one of the major growing joint problems. MSCs show differential ex vivo …

Immunosuppressive potential evaluation of synovial fluid mesenchymal stem cells grown on 3D scaffolds as an alternative source of MSCs for osteoarthritis cartilage …

F Paradiso, S Lenna, R Isbell… - Frontiers in …, 2022 - frontiersin.org
Osteoarthritis (OA) is a chronic degenerative joint disease, leading cause of disability in
older adults and leads to pain, reduced mobility, and decreased quality of life. Mesenchymal …

Allogeneic chondrogenic‐induced mesenchymal stem cells for the treatment of tarsometatarsal lameness in horses

RPC Coomer, JA Terschuur, MC Pressanto… - Veterinary …, 2024 - Wiley Online Library
Objective To assess the efficacy of commercial intra‐articular blood‐derived allogeneic‐
induced mesenchymal stem cells (CIMSCs) to treat tarsometatarsal lameness in horses …

Effects of Conditioned Media From Human Umbilical Cord-Derived Mesenchymal Stem Cells on Tenocytes From Degenerative Rotator Cuff Tears in an Interleukin 1β …

MJ Lee, K Park, S Yeon Lee, KH Jang… - … Journal of Sports …, 2024 - journals.sagepub.com
Background: Evidence suggests that mesenchymal stem cells (MSCs) are safe for treating
different tendinopathies. Synovial fluid is a pooled environment of biomarkers from the …

Mesenchymal Stem Cells Therapeutic Applications in Cartilage Regeneration

MB Gugjoo - Therapeutic Applications of Mesenchymal Stem Cells …, 2022 - Springer
Among various joint affections, osteoarthritis is one of the most common joint problems
reported in animals. Currently, no effective treatment is available that can treat the condition …

Estudio de mediadores relacionados con las propiedades inmunes de las células madre mesenquimales (MSCs) equinas bajo la influencia de diversos factores

I Gascón Mateo, L Barrachina Porcar… - zaguan.unizar.es
Las células madre mesenquimales (MSCs) son células madre adultas de origen
mesodérmico que, tanto en la especie humana como en las especies animales, presentan …