Nanoscale metal–organic frameworks for therapeutic, imaging, and sensing applications

K Lu, T Aung, N Guo, R Weichselbaum… - Advanced …, 2018 - Wiley Online Library
Nanotechnology has played an important role in drug delivery and biomedical imaging over
the past two decades. In particular, nanoscale metal–organic frameworks (nMOFs) are …

Harnessing albumin as a carrier for cancer therapies

EN Hoogenboezem, CL Duvall - Advanced drug delivery reviews, 2018 - Elsevier
Serum albumin, a natural ligand carrier that is highly concentrated and long-circulating in
the blood, has shown remarkable promise as a carrier for anti-cancer agents. Albumin is …

Magnetic nanoparticles as MRI contrast agents

A Avasthi, C Caro, E Pozo‑Torres, MP Leal… - … for electrochemical and …, 2020 - Springer
Iron oxide nanoparticles (IONPs) have emerged as a promising alternative to conventional
contrast agents (CAs) for magnetic resonance imaging (MRI). They have been extensively …

Spinel ferrite nanoparticles and nanocomposites for biomedical applications and their toxicity

KK Kefeni, TAM Msagati, TTI Nkambule… - Materials Science and …, 2020 - Elsevier
This review focuses on the biomedical applications and toxicity of spinel ferrite nanoparticles
(SFNPs) with more emphasis on the recently published work. A critical review is provided on …

Gadolinium-based contrast agent accumulation and toxicity: an update

J Ramalho, RC Semelka, M Ramalho… - American Journal …, 2016 - Am Soc Neuroradiology
In current practice, gadolinium-based contrast agents have been considered safe when
used at clinically recommended doses in patients without severe renal insufficiency. The …

Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine

A Akbarzadeh, M Samiei, S Davaran - Nanoscale research letters, 2012 - Springer
Finally, we have addressed some relevant findings on the importance of having well-defined
synthetic strategies developed for the generation of MNPs, with a focus on particle formation …

Iron oxide nanoparticle based contrast agents for magnetic resonance imaging

Z Shen, A Wu, X Chen - Molecular pharmaceutics, 2017 - ACS Publications
Magnetic iron oxide nanoparticles (MIONs) have attracted enormous attention due to their
wide applications, including for magnetic separation, for magnetic hyperthermia, and as …

Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

Classification and basic properties of contrast agents for magnetic resonance imaging

CFGC Geraldes, S Laurent - Contrast media & molecular …, 2009 - Wiley Online Library
A comprehensive classification of contrast agents currently used or under development for
magnetic resonance imaging (MRI) is presented. Agents based on small chelates …

MRI contrast agents: basic chemistry and safety

D Hao, T Ai, F Goerner, X Hu… - Journal of Magnetic …, 2012 - Wiley Online Library
Magnetic resonance imaging (MRI) contrast agents are pharmaceuticals used widely in MRI
examinations. Gadolinium‐based MRI contrast agents (GBCAs) are by far the most …