[HTML][HTML] Bacteria and bacterial derivatives as delivery carriers for immunotherapy
There is growing interest in the role of microorganisms in human health and disease, with
evidence showing that new types of biotherapy using engineered bacterial therapeutics …
evidence showing that new types of biotherapy using engineered bacterial therapeutics …
Biomimetic hybrid membrane-based nanoplatforms: synthesis, properties and biomedical applications
The rapid clearance and capture by the immune system pose a big challenge in targeted
drug delivery using nanocarriers. Cell membrane coating endows nanoplatforms with …
drug delivery using nanocarriers. Cell membrane coating endows nanoplatforms with …
Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …
Carcinogenesis and therapeutics: the microbiota perspective
Cancer arises from the acquisition of multiple genetic and epigenetic changes in host cells
over the span of many years, promoting oncogenic traits and carcinogenesis. Most cancers …
over the span of many years, promoting oncogenic traits and carcinogenesis. Most cancers …
Microbes as medicines: harnessing the power of bacteria in advancing cancer treatment
Conventional anti-cancer therapy involves the use of chemical chemotherapeutics and
radiation and are often non-specific in action. The development of drug resistance and the …
radiation and are often non-specific in action. The development of drug resistance and the …
Bacteria‐mediated tumor therapy via photothermally‐programmed cytolysin a expression
L Wang, W Qin, W Xu, F Huang, X **e, F Wang, L Ma… - Small, 2021 - Wiley Online Library
By leveraging the ability of bacteria to express therapeutic protein cytolysin A (ClyA) through
plasmid transformation, a thermally‐activated biohybrid (TAB@ Au) is constructed by …
plasmid transformation, a thermally‐activated biohybrid (TAB@ Au) is constructed by …
16S rRNA gene primer choice impacts off-target amplification in human gastrointestinal tract biopsies and microbiome profiling
T Deissová, M Zapletalová, L Kunovský, R Kroupa… - Scientific Reports, 2023 - nature.com
Abstract 16S rRNA amplicon sequencing or, more recently, metatranscriptomic analysis are
currently the only preferred methods for microbial profiling of samples containing a …
currently the only preferred methods for microbial profiling of samples containing a …
In situ delivery of biobutyrate by probiotic Escherichia coli for cancer therapy
CJ Chiang, YH Hong - Scientific Reports, 2021 - nature.com
Butyrate has a bioactive function to reduce carcinogenesis. To achieve targeted cancer
therapy, this study developed bacterial cancer therapy (BCT) with butyrate as a payload. By …
therapy, this study developed bacterial cancer therapy (BCT) with butyrate as a payload. By …
Advances in bacterial cancer therapies using synthetic biology
Synthetic biology aims to apply engineering principles to biology by modulating the behavior
of living organisms. An emerging application of this field is the engineering of bacteria as a …
of living organisms. An emerging application of this field is the engineering of bacteria as a …
The prospects for the therapeutic implications of genetically engineered probiotics
SF Mazhar, M Afzal, A Almatroudi, S Munir… - Journal of Food …, 2020 - Wiley Online Library
The interest in the therapeutic use of probiotic microorganisms has been increased during
the last decade although the doubts have ascended about the probiotics mainly because …
the last decade although the doubts have ascended about the probiotics mainly because …