Electrospun fiber-based strategies for controlling early innate immune cell responses: towards immunomodulatory mesh designs that facilitate robust tissue repair

D Venugopal, S Vishwakarma, I Kaur, S Samavedi - Acta Biomaterialia, 2023 - Elsevier
Electrospun fibrous meshes are widely used for tissue repair due to their ability to guide a
host of cell responses including phenotypic differentiation and tissue maturation. A critical …

Electrospun fiber scaffolds for engineering glial cell behavior to promote neural regeneration

DL Puhl, JL Funnell, DW Nelson, MK Gottipati… - Bioengineering, 2020 - mdpi.com
Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …

Real-time monitoring of mono-and dual-species biofilm formation and eradication using microfluidic platform

VN Tran, F Khan, W Han, M Luluil, VG Truong… - Scientific Reports, 2022 - nature.com
In a human host, bacterial Staphylococcus aureus and fungal Candida albicans pathogens
form a mixed biofilm that causes severe mortality and morbidity. However, research on the …

3D imaging and quantification of PLL coated fluorescent ZnO NP distribution and ROS accumulation using laser scanning confocal microscopy

A Dey, S Gare, S Swain, P Bhattacharya… - AIChE …, 2022 - Wiley Online Library
Investigations on nanomedicine involve conventional two dimensional (2D) imaging
techniques for observing the nanoparticle internalization at a single time point where various …

Potent particle-based vehicles for growth factor delivery from electrospun meshes: Fabrication and functionalization strategies for effective tissue regeneration

GS Shaw, S Samavedi - ACS Biomaterials Science & Engineering, 2021 - ACS Publications
Functionalization of electrospun meshes with growth factors (GFs) is a common strategy for
guiding specific cell responses in tissue engineering. GFs can exert their intended biological …

Three-dimensional tracking of intracellular calcium and redox state during real-time control in a hypoxic gradient in microglia culture: Comparison of the channel …

V Dhyani, S Kumar, SR Manne, I Kaur… - ACS Chemical …, 2023 - ACS Publications
Real-time three-dimensional (3-D) imaging is crucial for quantifying correlations among
various molecules under acute ischemic stroke. Insights into such correlations may be …

Map** of structural arrangement of cells and collective calcium transients: an integrated framework combining live cell imaging using confocal microscopy and …

S Gare, S Chel, TK Abhinav, V Dhyani… - Integrative …, 2022 - academic.oup.com
Abstract Live cell calcium (Ca2+) imaging is one of the important tools to record cellular
activity during in vitro and in vivo preclinical studies. Specially, high-resolution microscopy …

Non-prophylactic resveratrol-mediated protection of neurite integrity under chronic hypoxia is associated with reduction of Cav1. 2 channel expression and calcium …

D Saha, S Vishwakarma, RK Gupta, A Pant… - Neurochemistry …, 2023 - Elsevier
Cellular hypoxia is a major cause of oxidative stress, culminating in neuronal damage in
neurodegenerative diseases. Numerous ex vivo studies have implicated that hypoxia …

A computational model to uncover the biophysical underpinnings of neural firing heterogeneity in dissociated hippocampal cultures

V Dhyani, K George, S Gare, KV Venkatesh… - …, 2023 - Wiley Online Library
Abstract Calcium (Ca2+) imaging reveals a variety of correlated firing in cultures of
dissociated hippocampal neurons, pinpointing the non‐synaptic paracrine release of …

Expression, characterization, and application of human-like recombinant gelatin

X Song, T Chu, W Shi, J He - Bioresources and Bioprocessing, 2024 - Springer
Gelatin is a product obtained through partial hydrolysis and thermal denaturation of
collagen, belonging to natural biopeptides. With irreplaceable biological functions in the …