[HTML][HTML] The biology, function, and applications of exosomes in cancer

J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …

The biology and function of exosomes in cancer

R Kalluri - The Journal of clinical investigation, 2016 - jci.org
Humans circulate quadrillions of exosomes at all times. Exosomes are a class of
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …

The role of exosomes in cancer metastasis

TB Steinbichler, J Dudás, H Riechelmann… - Seminars in cancer …, 2017 - Elsevier
Exosomes are small membrane vesicles with a size ranging from 40 to 100 nm. They can
serve as functional mediators in cell interaction leading to cancer metastasis. Metastasis is a …

Role of epithelial-mesenchymal transition in retinal pigment epithelium dysfunction

M Zhou, JS Geathers, SL Grillo, SR Weber… - Frontiers in cell and …, 2020 - frontiersin.org
Retinal pigment epithelial (RPE) cells maintain the health and functional integrity of both
photoreceptors and the choroidal vasculature. Loss of RPE differentiation has long been …

Metastatic breast cancer: the potential of miRNA for diagnosis and treatment monitoring

A McGuire, JAL Brown, MJ Kerin - Cancer and metastasis reviews, 2015 - Springer
Breast cancer affects approximately 12% women worldwide and results in 14% of all cancer-
related fatalities. Breast cancer is commonly categorized into one of four main subtypes …

The role of EMT and MET in cancer dissemination

J Banyard, DR Bielenberg - Connective tissue research, 2015 - Taylor & Francis
Metastatic cancer cells are lethal. Understanding the molecular mechanisms that bolster the
conversion from benign to malignant progression is key for treating these heterogeneous …

[HTML][HTML] Emerging roles of cystathionine β-synthase in various forms of cancer

K Ascenção, C Szabo - Redox biology, 2022 - Elsevier
The expression of the reverse transsulfuration enzyme cystathionine-β-synthase (CBS) is
markedly increased in many forms of cancer, including colorectal, ovarian, lung, breast and …

[HTML][HTML] The extracellular matrix in pancreatic cancer: description of a complex network and promising therapeutic options

B Ferrara, C Pignatelli, M Cossutta, A Citro, J Courty… - Cancers, 2021 - mdpi.com
Simple Summary This review depicts the principal mechanisms involved in the process of
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …

Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p

G Ding, L Zhou, Y Qian, M Fu, J Chen, J Chen… - …, 2015 - pmc.ncbi.nlm.nih.gov
It has been reported tumor-derived exosomes can transfer miRNAs to recipient cells in the
tumor microenvironment, promoting tumor invasion and metastasis. The present research …