After fertilization, the quiescent zygote experiences a burst of genome activation that initiates
a short-lived totipotent state. Understanding the process of totipotency in human cells would …

Studying tissue composition and function in non-human primates (NHPs) is crucial to
understand the nature of our own species. Here we present a large-scale cell transcriptomic …

Teratoma, due to its remarkable ability to differentiate into multiple cell lineages, is a
valuable model for studying human embryonic development. The similarity of the gene …

Glioblastoma (GBM) cells are highly heterogeneous and invasive, leading to treatment
resistance and relapse. However, the molecular regulation in and distal to tumors remains …

The mammalian nervous system controls complex functions through highly specialized and
interacting structures. Single-cell sequencing can provide information on cell-type-specific …

Axolotl (Ambystoma mexicanum) is an excellent model for investigating regeneration, the
interaction between regenerative and developmental processes, comparative genomics …

The characteristics of neonatal immune cells display intrinsic differences compared with
adult immune cells. Therefore, a comprehensive analysis of key gene expression regulation …

Mesenchymal stem/stromal cells derived from placenta (PMSCs) are an attractive source for
regenerative medicine because of their multidifferentiation potential and immunomodulatory …

Burn injuries often leave behind a “stasis zone”, a region of tissue critically important for
determining both the severity of the injury and the potential for recovery. To understand the …

Spinal cord injury (SCI) impairs the central nervous system and induces the myelin‐sheath‐
deterioration because of reactive oxygen species (ROS), further hindering the recovery of …