Multi-parent populations in crops: a toolbox integrating genomics and genetic map** with breeding
Crop populations derived from experimental crosses enable the genetic dissection of
complex traits and support modern plant breeding. Among these, multi-parent populations …
complex traits and support modern plant breeding. Among these, multi-parent populations …
Systems genetics approaches to understand complex traits
M Civelek, AJ Lusis - Nature Reviews Genetics, 2014 - nature.com
Abstract Systems genetics is an approach to understand the flow of biological information
that underlies complex traits. It uses a range of experimental and statistical methods to …
that underlies complex traits. It uses a range of experimental and statistical methods to …
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
The extent to which low‐frequency (minor allele frequency (MAF) between 1–5%) and rare
(MAF≤ 1%) variants contribute to complex traits and disease in the general population is …
(MAF≤ 1%) variants contribute to complex traits and disease in the general population is …
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition
The amygdala processes positive and negative valence and contributes to addiction, but the
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas of …
cell-type-specific gene regulatory programs involved are unknown. We generated an atlas of …
[HTML][HTML] Tackling the climate, biodiversity and pollution emergencies by making peace with nature 50 years after the Stockholm Conference
IA Baste, RT Watson - Global Environmental Change, 2022 - Elsevier
Today's increasingly unequal and resource intensive development model degrades and
surpasses Earth's finite capacity to sustain human well-being. Society must restore this …
surpasses Earth's finite capacity to sustain human well-being. Society must restore this …
Epigenetics of atherosclerosis: emerging mechanisms and methods
Atherosclerosis is a vascular pathology characterized by inflammation and plaque build-up
within arterial vessel walls. Vessel occlusion, often occurring after plaque rupture, can result …
within arterial vessel walls. Vessel occlusion, often occurring after plaque rupture, can result …
Quantitative trait locus map** methods for diversity outbred mice
DM Gatti, KL Svenson, A Shabalin… - G3: Genes …, 2014 - academic.oup.com
Genetic map** studies in the mouse and other model organisms are used to search for
genes underlying complex phenotypes. Traditional genetic map** studies that employ …
genes underlying complex phenotypes. Traditional genetic map** studies that employ …
Genome-wide scan demonstrates significant linkage for male sexual orientation
BackgroundFindings from family and twin studies support a genetic contribution to the
development of sexual orientation in men. However, previous studies have yielded …
development of sexual orientation in men. However, previous studies have yielded …
Genetic properties of the MAGIC maize population: a new platform for high definition QTL map** in Zea mays
Abstract Background Maize (Zea mays) is a globally produced crop with broad genetic and
phenotypic variation. New tools that improve our understanding of the genetic basis of …
phenotypic variation. New tools that improve our understanding of the genetic basis of …
[HTML][HTML] Limited haplotype diversity underlies polygenic trait architecture across 70 years of wheat breeding
Background Selection has dramatically shaped genetic and phenotypic variation in bread
wheat. We can assess the genomic basis of historical phenotypic changes, and the potential …
wheat. We can assess the genomic basis of historical phenotypic changes, and the potential …