Artificial intelligence (AI) and machine learning have significantly influenced many facets of
the healthcare sector. Advancement in technology has paved the way for analysis of big …

High inter-patient variability and high spatial heterogeneity are features of colorectal cancer
(CRC). This may influence the molecular characterization of tumor tissue, now mandatory for …

Simple Summary Metastatic colorectal cancer is a complex, prevalent, and life-threatening
disease influenced by various factors that affect its progression, evolution, and treatment …

Currently, there is a crucial need for novel diagnostic and prognostic biomarkers with high
specificity and sensitivity in patients with colorectal cancer. A “liquid biopsy” is characterized …

Screening for anaplastic lymphoma kinase (ALK) rearrangements is a very important
process in treatment decision making for advanced non-small-cell lung cancer (NSCLC) …

Background Tumor molecular profile analysis by Next Generation Sequencing technology is
currently widely applied in clinical practice and has enabled the detection of predictive …

Purpose Next-generation sequencing (NGS) can facilitate precision medicine approaches in
metastatic colorectal cancer (mCRC) patients. We investigated the molecular profiling of …

The updated 2016 World Health Organization (WHO) classification system for gliomas
integrates molecular alterations and histology to provide a greater diagnostic and prognostic …

The establishment of precision medicine in cancer patients requires the study of several
biomarkers. Single-gene testing approaches are limited by sample availability and …

Colorectal cancer (CRC) is a malignancy with high metastatic rates. The mechanism of miR-
128 on the regulation of Ribophorin-II (RPN2) in CRC cells was explored in the present …