19F NMR has emerged as a powerful tool in drug discovery, particularly in fragment-based
screens. The favorable magnetic resonance properties of the fluorine-19 nucleus, the …

The 19F isotope is 100% naturally abundant and is the second most sensitive and stable
NMR-active nucleus. Unlike the ubiquitous hydrogen atom, fluorine is nearly absent in …

As the protein databank (PDB) recently passed the cap of 123 456 structures, it stands more
than ever as an important resource not only to analyze structural features of specific …

Ligand-based fluorine NMR screening has gained popularity in drug discovery projects
during the past decade and has become a powerful methodology to produce high quality …

Hydrogen‐bonding interactions play an important role in many chemical and biological
systems. Fluorine acting as a hydrogen‐bond acceptor in intermolecular and intramolecular …

The high‐voltage stability of electrolytes profoundly determines electrochemical reactions,
which is still one of the major obstacles for develo** advanced Al‐ion batteries (AIBs) …

For more than three decades, the ability of a fluorine atom involved in a C–F bond to act as a
hydrogen-bond acceptor has been a controversial issue. Throughout the years, more and …

Two radical-based approaches have been developed to effect the trifluoromethylation of aryl
C–H bonds in native peptides either using stoichiometric oxidant or visible light photoredox …

Anisole and fluoroanisoles display distinct conformational preferences, as evident from a
survey of their crystal structures. In addition to altering the free ligand conformation, various …

Magnesium (Mg) metal batteries exhibit great potential as energy storage systems beyond
lithium, owing to their inherent safety, material sustainability, and low cost. However, their …