Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and
synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central …

Studying the epidemiology of fibromyalgia (FM) is very important to understand the impact of
this disorder on persons, families and society. The recent modified 2010 classification …

Use of chronic opioid therapy for chronic noncancer pain has increased substantially. The
American Pain Society and the American Academy of Pain Medicine commissioned a …

This practical book has given tens of thousands of clinicians and students a comprehensive
introduction to mindfulness and its clinical applications. The book describes the …

Central sensitization (CS) has been proposed as a common pathophysiological mechanism
to explain related syndromes for which no specific organic cause can be found. The term …

Objectives The primary aim was to assess the psychometric properties (including internal
consistency, construct validity, reproducibility, and factor structure) of the Central …

BACKGROUND: In order to clarify the classification of physical complaints not attributable to
verifiable, conventionally defined diseases, a new diagnosis of bodily distress syndrome …

Signs of lower urinary tract (LUT) disease in domestic cats can be acute or chronic, and can
result from variable combinations of abnormalities within the lumen of the LUT, the …

Twin studies are becoming popular to investigate risk factors for low back pain (LBP)
because they consider the genetic factor and allow for more precise estimates of risks. We …

Background Many musculoskeletal pain conditions are characterized by hypersensitivity,
which is induced by central sensitization (CS). A questionnaire, the Central Sensitization …