The article aims to introduce computer scientists to the new field of bioinformatics. This area
has arisen from the needs of biologists to utilize and help interpret the vast amounts of data …

Constraint programming is a powerful paradigm for solving combinatorial search problems
that draws on a wide range of techniques from artificial intelligence, computer science …

A method is presented for automated best-matching alignment of three-dimensional models
represented by ensembles of points. A normalized spatial discrepancy (NSD) is introduced …

The key enzyme in coronavirus polyprotein processing is the viral main proteinase, M pro, a
protein with extremely low sequence similarity to other viral and cellular proteinases. Here …

Allergenic proteins from very different environmental sources have similar sequences and
structures. This fact may account for multiple allergen syndromes, whereby a myriad of …

The structures of ribosomal proteins and their interactions with RNA have been examined in
the refined crystal structure of the Haloarcula marismortui large ribosomal subunit. The …

The folding degree index (Estrada, Bioinformatics 2002; 18: 697–704) is extended to
account for the contribution of amino acids to folding. First, the mathematical formalism for …

This article investigates aspects of pairwise and multiple structure comparison, and the
problem of automatically discover common patterns in a set of structures. Descriptions and …

Background Similarity of sequences is a key mathematical notion for Classification and
Phylogenetic studies in Biology. It is currently primarily handled using alignments. However …

Nup98 is a component of the nuclear pore that plays its primary role in the export of RNAs.
Nup98 is expressed in two forms, derived from alternate mRNA splicing. Both forms are …