Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z **, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Biomaterials with cancer cell-specific cytotoxicity: challenges and perspectives

Z Chu, W Wang, W Zheng, W Fu, Y Wang… - Chemical Society …, 2024 - pubs.rsc.org
Significant advances have been made in materials for biomedical applications, including
tissue engineering, bioimaging, cancer treatment, etc. In the past few decades …

Transvascular transport of nanocarriers for tumor delivery

X Li, Y Hu, X Zhang, X Shi, WJ Parak, A Pich - Nature Communications, 2024 - nature.com
Nanocarriers (NCs) play a crucial role in delivering theranostic agents to tumors, making
them a pivotal focus of research. However, the persistently low delivery efficiency of …

[HTML][HTML] Computer-aided nanodrug discovery: recent progress and future prospects

JJ Zheng, QZ Li, Z Wang, X Wang, Y Zhao… - Chemical Society …, 2024 - pubs.rsc.org
Nanodrugs, which utilise nanomaterials in disease prevention and therapy, have attracted
considerable interest since their initial conceptualisation in the 1990s. Substantial efforts …

Aggregable gold nanoparticles for cancer photothermal therapy

M Wu, Y **ao, R Wu, J Lei, T Li, Y Zheng - Journal of Materials …, 2024 - pubs.rsc.org
Photothermal therapy (PTT) is an important non-invasive cancer treatment method.
Enhancing the photothermal conversion efficiency (PCE) of photothermal agents (PTAs) and …

Liposomes-enabled cancer chemoimmunotherapy

L Zhang, J Shi, MH Zhu, Y Huang, Q Lu, P Sun… - Biomaterials, 2024 - Elsevier
Chemoimmunotherapy is an emerging paradigm in the clinic for treating several malignant
diseases, such as non-small cell lung cancer, breast cancer, and large B-cell lymphoma …

Boosting Theranostic Performance of AIEgens Using Nanocatalyzer for Robust Cancer Immunotherapy

Y Li, Z Du, Y Zhang, X Kang, J Song… - Advanced Functional …, 2024 - Wiley Online Library
High‐performance theranostic systems are of paramount importance for achieving precise
image‐guided cancer immunotherapy. Here, a novel nanoplatform is presented that …

Neutrophil Extracellular Traps‐Inhibiting and Fouling‐Resistant Polysulfoxides Potently Prevent Postoperative Adhesion, Tumor Recurrence, and Metastasis

J Wang, Y Wang, J Li, J Ying, Y Mu, X Zhang… - Advanced …, 2024 - Wiley Online Library
Peritoneal metastasis (PM) is considered one of the most dreaded forms of cancer
metastases for both patients and physicians. Aggressive cytoreductive surgery (CRS) is the …

Potential application of aptamers combined with DNA nanoflowers in neurodegenerative diseases

Z Hang, L Zhou, X Bian, G Liu, F Cui, H Du… - Ageing Research …, 2024 - Elsevier
The efficacy of neurotherapeutic drugs hinges on their ability to traverse the blood-brain
barrier and access the brain, which is crucial for treating or alleviating neurodegenerative …