Preterm patent ductus arteriosus: a continuing conundrum for the neonatologist?

N Evans - Seminars in Fetal and Neonatal Medicine, 2015 - Elsevier
How to manage the preterm patent ductus arteriosus (PDA) remains a conundrum. On the
one hand, physiology and statistical association with adverse outcomes suggest that it is …

Hemodynamic instability in the critically ill neonate: an approach to cardiovascular support based on disease pathophysiology

RE Giesinger, PJ McNamara - Seminars in perinatology, 2016 - Elsevier
Hemodynamic disturbance in the sick neonate is common, highly diverse in underlying
pathophysiology and dynamic. Dysregulated systemic and cerebral blood flow is …

Failure of ductus arteriosus closure is associated with increased mortality in preterm infants

S Noori, M McCoy, P Friedlich, B Bright, V Gottipati… - …, 2009 - publications.aap.org
OBJECTIVE. Because the standard of care has been to attempt to close the patent ductus
arteriosus in preterm neonates, there is a paucity of information on the outcome of patients …

Use of targeted neonatal echocardiography to prevent postoperative cardiorespiratory instability after patent ductus arteriosus ligation

A Jain, M Sahni, A El-Khuffash, E Khadawardi… - The Journal of …, 2012 - Elsevier
OBJECTIVES: To investigate the value of targeted neonatal echocardiography (TnECHO) in
predicting cardiorespiratory instability after patent ductus arteriosus (PDA) ligation, and to …

The role of patent ductus arteriosus ligation in bronchopulmonary dysplasia: reexamining a randomized controlled trial

R Clyman, G Cassady, JK Kirklin, M Collins… - The Journal of …, 2009 - Elsevier
OBJECTIVE: To reexamine data from a randomized controlled trial of prophylactic ductus
ligation to determine whether ligation contributes directly to the development of …

Surgical ligation versus percutaneous closure of patent ductus arteriosus in very low-weight preterm infants: which are the real benefits of the percutaneous approach …

A Rodríguez Ogando, I Planelles Asensio… - Pediatric …, 2018 - Springer
Percutaneous treatment of patent ductus arteriosus (PDA) in extreme premature infants is
technically difficult, and therefore, often not consider as an alternative to surgery. The main …

Patent ductus arteriosus, its treatments, and the risks of pulmonary morbidity

RI Clyman - Seminars in perinatology, 2018 - Elsevier
A persistent left-to-right shunt through a patent ductus arteriosus (PDA) increases the rate of
hydrostatic fluid filtration into the lung's interstitium, impairs pulmonary mechanics, and …

Hemodynamic dysfunction in neonatal sepsis

A Kharrat, A Jain - Pediatric Research, 2022 - nature.com
Cardiovascular disturbances are a frequent occurrence in neonatal sepsis. Preterm and
term infants are particularly vulnerable due to the unique features of their cardiovascular …

The role of patent ductus arteriosus and its treatments in the development of bronchopulmonary dysplasia

RI Clyman - Seminars in perinatology, 2013 - Elsevier
A persistent left-to-right shunt through a patent ductus arteriosus (PDA) increases the rate of
hydrostatic fluid filtration into the lung's interstitium, impairs pulmonary mechanics, and …

Patent ductus arteriosus in the preterm infant: to treat or not to treat?

S Noori - Journal of Perinatology, 2010 - nature.com
Pharmacological and/or surgical closure of a hemodynamically significant patent ductus
arteriosus (PDA) in the very preterm infant has been the standard of care over the past few …