Assessment of the evolution of cancer treatment therapies
Cancer therapy has been characterized throughout history by ups and downs, not only due
to the ineffectiveness of treatments and side effects, but also by hope and the reality of …
to the ineffectiveness of treatments and side effects, but also by hope and the reality of …
Antibody‐conjugated nanoparticles for biomedical applications
M Arruebo, M Valladares… - Journal of …, 2009 - Wiley Online Library
Nanoscience and Nanotechnology have found their way into the fields of Biotechnology and
Medicine. Nanoparticles by themselves offer specific physicochemical properties that they …
Medicine. Nanoparticles by themselves offer specific physicochemical properties that they …
Understanding the human antibody repertoire
AR Rees - MAbs, 2020 - Taylor & Francis
The origins of the various elements in the human antibody repertoire have been and still are
subject to considerable uncertainty. Uncertainty in respect of whether the various elements …
subject to considerable uncertainty. Uncertainty in respect of whether the various elements …
Monoclonal antibody humanness score and its applications
SH Gao, K Huang, H Tu, AS Adler - BMC biotechnology, 2013 - Springer
Background Monoclonal antibody therapeutics are rapidly gaining in popularity for the
treatment of a myriad of diseases, ranging from cancer to autoimmune diseases and …
treatment of a myriad of diseases, ranging from cancer to autoimmune diseases and …
Rapid identification and quantification of tumor cells using an electrocatalytic method based on gold nanoparticles
There is a high demand for simple, rapid, efficient, and user-friendly alternative methods for
the detection of cells in general and, in particular, for the detection of cancer cells. A …
the detection of cells in general and, in particular, for the detection of cancer cells. A …
Humanized non-human animals with restricted immunoglobulin heavy chain loci
L Macdonald, J McWhirter, S Stevens… - US Patent …, 2019 - Google Patents
Mice, embryos, cells, and tissues having a restricted immu noglobulin heavy chain locus and
an ectopic sequence encoding one or more ADAM6 proteins are provided. In various …
an ectopic sequence encoding one or more ADAM6 proteins are provided. In various …
Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses
H **ao, T Guo, M Yang, J Qi, C Huang, Y Hong, J Gu… - Cell Discovery, 2019 - nature.com
The isolation of human monoclonal antibodies with broadly neutralizing breadth can provide
a promising countermeasure for influenza A viruses infection. Most broadly neutralizing …
a promising countermeasure for influenza A viruses infection. Most broadly neutralizing …
Preparation of healing-promoting and fibrosis-inhibiting asymmetric poly (ethylene glycol-bL-phenylalanine)/cRGD-modified hyaluronate sponges and their …
C Feng, C Huang, J Huang, X Yang, Y Liu… - International Journal of …, 2024 - Elsevier
Acute or chromic bleeding, such as epistaxis, requires hemostatic materials to assist
hemostasis. Even in complex cases, hemostatic materials must have other functions …
hemostasis. Even in complex cases, hemostatic materials must have other functions …
Animal models and therapeutic molecules
The invention discloses methods for the generation of chimaeric human—non-human
antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and …
antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and …
Animal models and therapeutic molecules
The invention discloses methods for the generation of chimaeric human non-human
antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and …
antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and …