Resting-state functional MRI: everything that nonexperts have always wanted to know

H Lv, Z Wang, E Tong, LM Williams… - American Journal of …, 2018 - ajnr.org
Resting-state fMRI was first described by Biswal et al in 1995 and has since then been
widely used in both healthy subjects and patients with various neurologic, neurosurgical …

[HTML][HTML] The virtual epileptic patient: individualized whole-brain models of epilepsy spread

VK Jirsa, T Proix, D Perdikis, MM Woodman, H Wang… - Neuroimage, 2017 - Elsevier
Individual variability has clear effects upon the outcome of therapies and treatment
approaches. The customization of healthcare options to the individual patient should …

Macroscopic resting-state brain dynamics are best described by linear models

E Nozari, MA Bertolero, J Stiso, L Caciagli… - Nature biomedical …, 2024 - nature.com
It is typically assumed that large networks of neurons exhibit a large repertoire of nonlinear
behaviours. Here we challenge this assumption by leveraging mathematical models derived …

The dynamics of resting fluctuations in the brain: metastability and its dynamical cortical core

G Deco, ML Kringelbach, VK Jirsa, P Ritter - Scientific reports, 2017 - nature.com
In the human brain, spontaneous activity during resting state consists of rapid transitions
between functional network states over time but the underlying mechanisms are not …

Learning how network structure shapes decision-making for bio-inspired computing

M Schirner, G Deco, P Ritter - Nature communications, 2023 - nature.com
To better understand how network structure shapes intelligent behavior, we developed a
learning algorithm that we used to build personalized brain network models for 650 Human …

A graph signal processing perspective on functional brain imaging

W Huang, TAW Bolton, JD Medaglia… - Proceedings of the …, 2018 - ieeexplore.ieee.org
Modern neuroimaging techniques provide us with unique views on brain structure and
function; ie, how the brain is wired, and where and when activity takes place. Data acquired …

From maps to multi-dimensional network mechanisms of mental disorders

U Braun, A Schaefer, RF Betzel, H Tost… - Neuron, 2018 - cell.com
The development of advanced neuroimaging techniques and their deployment in large
cohorts has enabled an assessment of functional and structural brain network architecture at …

Amortized Bayesian inference on generative dynamical network models of epilepsy using deep neural density estimators

M Hashemi, AN Vattikonda, J Jha, V Sip… - Neural Networks, 2023 - Elsevier
Whole-brain modeling of epilepsy combines personalized anatomical data with dynamical
models of abnormal activities to generate spatio-temporal seizure patterns as observed in …

Inferring multi-scale neural mechanisms with brain network modelling

M Schirner, AR McIntosh, V Jirsa, G Deco, P Ritter - elife, 2018 - elifesciences.org
The neurophysiological processes underlying non-invasive brain activity measurements are
incompletely understood. Here, we developed a connectome-based brain network model …

Linking molecular pathways and large-scale computational modeling to assess candidate disease mechanisms and pharmacodynamics in Alzheimer's disease

L Stefanovski, P Triebkorn, A Spiegler… - Frontiers in …, 2019 - frontiersin.org
Introduction: While the prevalence of neurodegenerative diseases associated with dementia
such as Alzheimer's disease (AD) increases, our knowledge on the underlying mechanisms …